Depth of anesthesia during RSI and first-pass intubation success in emergency department adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective study uses BIS monitoring during rapid sequence intubation in adult emergency department patients to see if anesthetic depth correlates with first-pass success. The intubator remains blinded to BIS readings to avoid bias, while BIS is measured with a disposable forehead sensor. The goal is to identify whether deeper or lighter anesthesia at laryngoscopy affects the likelihood of successful first-pass intubation and related airway conditions. The findings could inform anesthesia practices in emergency airway management and potentially reduce complication rates associated with multiple intubation attempts. The study is conducted at Akdeniz University Hospital and includes adults 18 years and older undergoing RSI who have no frontal injuries preventing BIS sensor placement.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 years or older
* Patients undergoing rapid sequence intubation (RSI) in the emergency department
* No traumatic injury to the frontal region that would interfere with placement of the Bispectral Index (BIS) sensor

Exclusion Criteria:

* Age younger than 18 years
* Pregnant patients
* Patients with cardiac arrest or hemodynamic instability at the time of enrollment
* Patients intubated without the rapid sequence intubation (RSI) protocol
* Refusal to participate in the study (by the patient or, where applicable, a legally authorized representative)

Where it's running

• Akdeniz University Hospital
  Antalya, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Muhammed Türe, MD
• Email: erkangoksu@akdeniz.edu.tr
• Phone: +905054691764

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.