Clinical trial Recruiting at 1 site Observational

Deep Rectus Sheath Block in Abdominal Surgery

Official title: The Effectiveness of the Deep Rectus Sheath (Preperitoneal) Block for Postoperative Analgesia in Abdominal Surgery: A Prospective Observational Clinical Study

Run by San Giovanni di Dio Hospital · NCT07586462 · Data updated 2026-11-12

This study tests whether using the Deep Rectus Sheath block helps people recover better and manage pain after open or laparoscopic abdominal surgery.

Quick facts

Study typeObservational
SexAll
Enrollment60 (estimated)
SponsorSan Giovanni di Dio Hospital
Academic / other
Locations2 sites (Crotone and 1 other locations)
StatusRecruiting
StartedMay 2026
Main results expectedMay 2027
Study endsMay 2027
Registry record updatedMay 22, 2026
Trial IDNCT07586462 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18+) undergoing open or laparoscopic abdominal surgery, with ASA I–III, and able to provide informed consent.

Probably not a fit

Patients receiving analgesic strategies other than the DRS block or those with contraindications to locoregional anesthesia may see no added benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study in adults undergoing abdominal surgery where analgesic care is chosen by the treating team. Participants are grouped by whether they receive standard systemic analgesia, the Deep Rectus Sheath block, or other fascial plane blocks as part of routine care. Postoperative recovery and pain outcomes are collected, including QoR-15 at 24 hours, pain scores up to 48 hours, analgesic use, time to first analgesic, mobilization, and complications. The block, when used, is ultrasound-guided and delivered pre-incision or postoperatively, with data on technique and dosing recorded. No randomization is performed; analyses will compare outcomes across the different analgesic strategies in real-world practice.

Why it matters

Potential benefit: If the DRS block proves beneficial, patients may experience better pain control and faster recovery after abdominal surgery.

How similar studies have gone: Prior reports suggest regional blocks can improve pain and recovery in abdominal surgery, but this exact DRS approach is still being explored.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Patients undergoing abdominal surgery, either open or laparoscopic
* ASA physical status I-III
* Neuraxial or general anesthesia according to standard clinical practice
* Provision of informed consent to participate in the study

Exclusion Criteria:

* Refusal to provide informed consent
* Contraindications to locoregional anesthesia
* Known allergy to local anesthetic agents
* Coagulation disorders or incompatible anticoagulant therapy
* Infection at the injection site
* Cognitive impairment preventing reliable assessment of outcomes

Where it's running

  • Crotone Hospital
    Crotone, Italy
    Recruiting
  • Crotone Hospital
    Crotone, Italy
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.