Deep Rectus Sheath Block in Abdominal Surgery
Official title: The Effectiveness of the Deep Rectus Sheath (Preperitoneal) Block for Postoperative Analgesia in Abdominal Surgery: A Prospective Observational Clinical Study
Run by San Giovanni di Dio Hospital · NCT07586462 · Data updated 2026-11-12
This study tests whether using the Deep Rectus Sheath block helps people recover better and manage pain after open or laparoscopic abdominal surgery.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | San Giovanni di Dio Hospital Academic / other |
| Locations | 2 sites (Crotone and 1 other locations) |
| Status | Recruiting |
| Started | May 2026 |
| Main results expected | May 2027 |
| Study ends | May 2027 |
| Registry record updated | May 22, 2026 |
| Trial ID | NCT07586462 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) undergoing open or laparoscopic abdominal surgery, with ASA I–III, and able to provide informed consent.
✕Probably not a fit
Patients receiving analgesic strategies other than the DRS block or those with contraindications to locoregional anesthesia may see no added benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational study in adults undergoing abdominal surgery where analgesic care is chosen by the treating team. Participants are grouped by whether they receive standard systemic analgesia, the Deep Rectus Sheath block, or other fascial plane blocks as part of routine care. Postoperative recovery and pain outcomes are collected, including QoR-15 at 24 hours, pain scores up to 48 hours, analgesic use, time to first analgesic, mobilization, and complications. The block, when used, is ultrasound-guided and delivered pre-incision or postoperatively, with data on technique and dosing recorded. No randomization is performed; analyses will compare outcomes across the different analgesic strategies in real-world practice.
Why it matters
Potential benefit: If the DRS block proves beneficial, patients may experience better pain control and faster recovery after abdominal surgery.
How similar studies have gone: Prior reports suggest regional blocks can improve pain and recovery in abdominal surgery, but this exact DRS approach is still being explored.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Patients undergoing abdominal surgery, either open or laparoscopic * ASA physical status I-III * Neuraxial or general anesthesia according to standard clinical practice * Provision of informed consent to participate in the study Exclusion Criteria: * Refusal to provide informed consent * Contraindications to locoregional anesthesia * Known allergy to local anesthetic agents * Coagulation disorders or incompatible anticoagulant therapy * Infection at the injection site * Cognitive impairment preventing reliable assessment of outcomes
Where it's running
-
Crotone Hospital
Crotone, Italy Recruiting -
Crotone Hospital
Crotone, Italy Not yet recruiting
Study contacts
- Study coordinator: Tommaso Sorrentino, MD
- Email: dr.sorrentinotommaso@gmail.com
- Phone: +393277038017
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.