DBT-P program to help pregnant people manage strong emotions

Developing Pregnancy-specific Dialectical Behavior Therapy Skills to Promote Multigenerational Mental Health

Not applicable Interventional Duke University · NCT06963801

This study will see if a 10-week remote DBT skills program for pregnant people with emotion dysregulation can reduce stress and improve heart-rate regulation during pregnancy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
Ages18 Years to 45 Years
SexFemale
SponsorDuke University Academic / other
Locations1 site (Durham, North Carolina)
Trial IDNCT06963801 on ClinicalTrials.gov

What this trial studies

Pregnant participants with high emotion dysregulation scores are enrolled and complete clinic visits early, mid, and late in pregnancy for surveys, interviews, and heart-rate measures. Participants assigned to the intervention will join weekly remote DBT-P emotion-regulation skills groups for 10 weeks and complete daily mood and coping diary cards, while others receive usual care. The study compares changes in self-reported emotion regulation, stress and physiological markers (heart rate/RSA) across pregnancy and into the postpartum period. The investigators aim to determine whether targeting skill use in pregnancy improves postpartum maternal mental health and newborn neurobehavior.

Who should consider this trial

Good fit: People who are at least 12 weeks pregnant with a singleton pregnancy, fluent in English, and who score 88 or higher on an emotion dysregulation measure are ideal candidates.

Not a fit: People with active psychosis, a current drug or alcohol use disorder during pregnancy, imminent high suicide risk, major medical complications, or who cannot complete written measures are excluded and unlikely to benefit from this program.

Why it matters

Potential benefit: If successful, the program could lower maternal stress, improve heart-rate regulation, and support better postpartum mental health and early mother–infant co-regulation.

How similar studies have performed: DBT skills interventions have shown benefits for emotion dysregulation in non-pregnant adults, but adapting and testing DBT specifically during pregnancy is relatively new.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Emotion dysregulation score of 88 or above
* At least 12 weeks pregnant
* Singleton Pregnancy
* Fluent in English

Exclusion Criteria:

* Active psychosis
* Drug or alcohol use disorder during pregnancy
* High risk of an imminent suicide attempt
* Significant health complications (e.g., cancer)
* Illiterate and/or unable to independently complete and comprehend written measures

Where this trial is running

Durham, North Carolina

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Emotion DysregulationEmotion dysregulationPregnancyMaternal healthRSACopingStressDBT-P
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.