Daily topical inositol gel for breast pain after surgery

Evaluating the Effect of a Medical Device Based on Inositol in Improving Breast Pain

Not applicable Interventional Lo.Li.Pharma s.r.l · NCT07257770

This trial will try a daily topical inositol gel to see if it reduces breast pain in women after breast surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages18 Years to 70 Years
SexFemale
SponsorLo.Li.Pharma s.r.l Industry-sponsored
Locations1 site (Roma)
Trial IDNCT07257770 on ClinicalTrials.gov

What this trial studies

The study enrolls adult women (18–70) who report breast pain related to a surgical wound at least 15 days after breast surgery. Participants apply a medical device gel containing inositol to the affected area daily and record pain using a visual analogue scale (VAS). The primary approach is to compare pain scores before and after the local treatment over the study period. The trial is conducted at Policlinico Umberto I in Rome.

Who should consider this trial

Good fit: Women aged 18–70 who had breast surgery at least 15 days earlier and who are experiencing breast pain linked to the surgical wound are ideal candidates.

Not a fit: Patients on ongoing systemic or local pain therapy, pregnant women, minors, or those with breast pain not related to a surgical wound are unlikely to benefit from this intervention.

Why it matters

Potential benefit: If effective, the gel could offer a local, non‑systemic option to reduce postoperative breast pain.

How similar studies have performed: Topical inositol for postoperative mastalgia is largely novel and prior clinical evidence for this specific local application is limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Women aged between 18 and 70 years
* Women who underwent breast surgery at least 15 days prior
* Women experiencing breast pain associated with the surgical wound

Exclusion Criteria:

* Women under the age of 18
* Ongoing systemic and/or local pain therapy
* Pregnant women

Where this trial is running

Roma

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Mastalgiainositolbreast painmastalgia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.