Current medical approaches for managing adenomyosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a multicenter observational cohort combining retrospective and prospective enrollment to document real-world therapeutic choices for adenomyosis. No treatments are assigned by the protocol; investigators record clinical, imaging, and treatment data and follow patients over time to capture treatment persistence. Inclusion requires imaging or histologic confirmation and significant symptoms (pain or heavy bleeding), while patients with endometriosis or pregnancy are excluded. Collected data will be analyzed to identify the criteria guiding treatment selection in routine clinical practice across centers.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Age between 20 and 50 years; Instrumental (ultrasound or MRI) and/or histological diagnosis of adenomyosis; Adenomyosis-associated pain with a VAS score ≥ 4 and/or presence of heavy menstrual bleeding (HMB) defined as a score \> 100 on the Pictorial Blood Assessment Chart (PBAC); Provision of written informed consent to participate in the study; Willingness to be followed at the participating center for the entire duration of the study.

Exclusion Criteria:

Current or previous clinical and/or instrumental diagnosis of endometriosis; Suspected or confirmed pregnancy; Inability to understand the purpose of the study and to provide informed consent.

Where it's running

• Ospedale San Carlo
  Potenza, Italy Recruiting

Study contacts

• Study coordinator: Sergio Schettini
• Email: schettini@icloud.com
• Phone: +39 335424088

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.