Curcumin and astaxanthin to lower triglycerides and reduce low-level inflammation
Official title: Curcumin and Astaxanthin for Lowering Triglyceride Readings and Inflammation
Run by Medinutra LLC · NCT07063056 · Data updated 2026-11-12
This test will see if taking one daily capsule of curcumin or astaxanthin helps adults with moderately high triglycerides keep their levels in the normal range over six weeks.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 21 Years to 59 Years |
| Sex | All |
| Enrollment | 64 (estimated) |
| Sponsor | Medinutra LLC Academic / other |
| Locations | 1 site (Dublin, Ohio) |
| Status | Recruiting |
| Started | July 18, 2025 |
| Main results expected | September 25, 2026 |
| Study ends | September 25, 2026 |
| Registry record updated | July 14, 2026 |
| Trial ID | NCT07063056 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 21–59 years old with fasting triglycerides between 140 and 250 mg/dL who meet the study's health criteria (no uncontrolled diabetes, active liver disease, certain inflammatory or hormonal disorders, heavy alcohol use, smoking, extreme obesity, pregnancy, or breastfeeding) are ideal candidates.
✕Probably not a fit
People with uncontrolled diabetes, active liver disease, autoimmune inflammatory diseases, current smokers, those drinking more than five alcoholic drinks per week, individuals with BMI over 37, or pregnant or breastfeeding people are unlikely to benefit or may be excluded.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults aged 21–59 with fasting triglyceride readings of 140–250 mg/dL will be assigned to take one capsule daily of Longvida curcumin (full or half dose), astaxanthin, or a placebo for six weeks. Fasting serum triglycerides and several blood markers related to low-level inflammation will be measured at baseline and after six weeks. Each supplement is compared against placebo to determine whether it helps maintain triglyceride readings within the normal range with minimal side effects.
Why it matters
Potential benefit: If successful, these supplements could provide a low-cost, low-side-effect option to help people with moderately high triglycerides maintain healthier lipid levels and reduce low-level inflammation.
How similar studies have gone: Small clinical and preclinical studies have reported modest lipid-lowering and anti-inflammatory effects for curcumin and astaxanthin, but larger, well-controlled trials are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Triglyceride reading of 140-250 mg/dL * Age 21-59 Exclusion Criteria: * Uncontrolled diabetes * Hypothyroidism or other hormonal problems that have not stabilized * Any liver diseases being actively treated * Cancer * Renal dialysis use * Rheumatoid arthritis and related issues like lupus * Inflammatory bowel disease * Smoking * Low blood pressure * Having more than 5 alcoholic drinks per week * Extreme obesity (BMI over 37) * Pregnancy or lactation
Where it's running
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Medinutra LLC
Dublin, Ohio, United States Recruiting
Study contacts
- Principal investigator: Robert DiSilvestro, Ph.D. — Medinutra LLC
- Study coordinator: Robert DiSilvestro, Ph.D.
- Email: nutritionstudy111@gmail.com
- Phone: 6143489375
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.