Cuff (intermittent) versus arterial-line (continuous) blood pressure monitoring during robot-assisted prostatectomy
Official title: Oscillometric Versus Intraarterial Blood Pressure Monitoring to Reduce Intraoperative Hypotension During Robot-Assisted Prostatectomy: A Non-Inferiority Randomized Trial
Run by University of Hamburg-Eppendorf · NCT07349186 · Data updated 2026-11-12
This will test whether regular cuff blood pressure checks work as well as a continuous arterial line to prevent low blood pressure during robot-assisted prostate removal in adult men.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | Men only |
| Enrollment | 210 (estimated) |
| Sponsor | University of Hamburg-Eppendorf Academic / other |
| Locations | 1 site (Hamburg, Free and Hanseatic City of Hamburg) |
| Status | Recruiting |
| Started | January 29, 2026 |
| Main results expected | January 2027 |
| Study ends | February 2027 |
| Registry record updated | February 2, 2026 |
| Trial ID | NCT07349186 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adult men (≥18 years) scheduled for elective robot-assisted (Da Vinci) radical prostatectomy in steep Trendelenburg who were planned to have intraarterial blood pressure monitoring but for whom an arterial line is not mandatory are ideal candidates.
✕Probably not a fit
Patients who require mandatory arterial-line monitoring for clinical reasons or who are enrolled in another interventional trial affecting blood pressure management are unlikely to benefit from this comparison.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
PROST-BP is a prospective, single-center, randomized, patient-blinded non-inferiority trial comparing intermittent oscillometric (cuff) blood pressure monitoring with continuous intraarterial monitoring during robot-assisted radical prostatectomy in steep Trendelenburg position. Eligible adult men who are scheduled for planned intraarterial monitoring are randomized to receive either standard arterial-line monitoring or intermittent cuff measurements during surgery. The primary outcome is the occurrence or burden of intraoperative hypotension, with monitoring and management performed according to standardized anesthetic protocols. The trial is conducted at the University Medical Center Hamburg-Eppendorf and enrolls patients who do not require mandatory arterial monitoring for clinical reasons.
Why it matters
Potential benefit: If successful, patients could avoid an invasive arterial line during this surgery without increasing their risk of intraoperative low blood pressure.
How similar studies have gone: Previous comparisons of noninvasive oscillometric versus invasive arterial monitoring in other surgical settings have shown mixed results, and this specific robot-assisted, steep Trendelenburg setting has been less extensively studied.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * male patient ≥18 years * scheduled for elective robot-assisted (Da Vinci) radical prostatectomy in steep Trendelenburg position * planned intraarterial blood pressure monitoring Exclusion Criteria: * patients in whom the attending anesthesiologist considers intraarterial blood pressure monitoring to be mandatory for clinical reasons * patients participating in another interventional trial likely to influence intraoperative blood pressure management
Where it's running
-
University Medical Center Hamburg-Eppendorf
Hamburg, Free and Hanseatic City of Hamburg, Germany Recruiting
Study contacts
- Study coordinator: Alina Bergholz
- Email: a.bergholz@uke.de
- Phone: 004940 7410 0
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Remimazolam vs propofol for stable blood pressure during thoracic/abdominal endovascular aortic repair
This trial tests whether remimazolam keeps blood pressure steadier than propofol during TEVAR or EVAR in adults.
-
Remimazolam vs. Propofol for Maintaining Anesthesia During Major Liver Resection
This study tests whether remimazolam keeps blood pressure steadier than propofol during major liver surgery in adults.
-
Remimazolam versus Midazolam for anesthesia induction in older adults
This observational study compares remimazolam and midazolam when inducing anesthesia in people aged 65 and older undergoing elective non-cardiac surgery to see which provides better stability and safety.
-
Keep blood pressure at 85 or more during surgery to prevent delirium in older adults with hypertension
In older adults with high blood pressure undergoing non-heart surgery, researchers test if keeping mean arterial pressure at or above 85 mmHg during surgery reduces postoperative delirium.
-
Internal Jugular Vein Collapsibility to Predict Hypotension in Older Adults Undergoing Laparoscopic Colorectal Surgery
This study tests whether measuring the internal jugular vein collapsibility index can predict intraoperative hypotension in patients aged 60 and older undergoing elective laparoscopic colorectal surgery.
-
Can neck vein ultrasound predict low blood pressure and kidney injury during abdominal surgery?
This observational study tests whether ultrasound measurements of the internal jugular vein can help predict low blood pressure during anesthesia induction and possible kidney injury after abdominal surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.