CT imaging comparison of GMA-Tulip, I-gel, and LMA Supreme laryngeal masks
An in Vivo CT Imaging Study After Insertion of the LMA Supreme, I-gel, and GMA-Tulip Airway Devices Under General Anesthesia (GLAM-II)
This project will use CT scans to see if three laryngeal masks (GMA-Tulip, I-gel, and LMA Supreme) sit differently and compress surrounding tissues in adults having CT-guided procedures under general anesthesia.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 9 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Zhejiang Cancer Hospital Academic / other |
| Locations | 2 sites (Hangzhou, Zhejiang and 1 other locations) |
| Trial ID | NCT07196696 on ClinicalTrials.gov |
What this trial studies
Adults aged 18–75 (ASA I–II, BMI <30) scheduled for CT interventional therapy will be randomly assigned to receive one of three supraglottic airway devices—LMA Supreme, I-gel, or GMA-Tulip—inserted by experienced anesthesiologists. After standardized induction of general anesthesia and muscle relaxation, each device will be placed and in vivo neck CT imaging will be performed to record insertion depth, anatomical alignment, and local tissue compression. Investigators will compare device position and relationships to adjacent structures on CT to identify consistent misalignments or compression patterns. Findings are intended to provide anatomical evidence to help optimize laryngeal mask choice and reduce placement-related ventilation problems and complications.
Who should consider this trial
Good fit: Adults 18–75 years old with ASA physical status I–II, BMI under 30 kg/m², scheduled for CT interventional therapy, and able to give informed consent.
Not a fit: Patients with head/neck or airway anatomical abnormalities, those enrolled in other clinical studies, or those outside the specified age/BMI criteria are unlikely to benefit from this protocol.
Why it matters
Potential benefit: If successful, this could help clinicians choose the laryngeal mask that best matches patient anatomy and reduce airway-related complications.
How similar studies have performed: Previous studies using endoscopy or radiography have described supraglottic device positioning, but direct in vivo CT comparisons of these three devices are relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 18-75 years, scheduled for CT interventional therapy; * Aged 18-75 years, scheduled for CT interventional therapy; * Body Mass Index (BMI) \<30 kg/m²; * Good communication and cooperation, with voluntary signing of the informed consent form. Exclusion Criteria: * Presence of head/neck or airway anatomical abnormalities (e.g., laryngeal cartilage malformation, Grade III tonsillar hypertrophy, tongue hypertrophy, cervical spine malformation) that may affect laryngeal mask insertion or CT imaging evaluation; * Current participation in other clinical studies.
Where this trial is running
Hangzhou, Zhejiang and 1 other locations
- Ethics Committee of Zhejiang Cancer Hospital — Hangzhou, Zhejiang, China (Recruiting)
- Jiangling Wang — Hangzhou, Zhejiang, China (Recruiting)
Study contacts
- Principal investigator: Jiangling Wang, Dr — Zhejiang Cancer Hospital
- Study coordinator: Xiaochun Jin, M.D
- Email: ec@zjcc.org.cn
- Phone: +86 571-88122564
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.