Cruciate incision versus saucerization for draining diabetic carbuncle, both followed by vacuum-assisted closure
Comparison of Wound Healing for Diabetic Carbuncle Treated With Incision and Drainage Technique Using Cruciate Incision vs Saucerization Technique Both Followed by Vacuum Assisted Closure.
This trial will test whether a cruciate incision or saucerization—each followed by vacuum-assisted closure (VAC)—causes less blood loss and faster healing in people aged 25–70 with diabetic carbuncles.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 124 (estimated) |
| Ages | 25 Years to 70 Years |
| Sex | All |
| Sponsor | King Edward Medical University Academic / other |
| Locations | 1 site (Lahore, Punjab Province) |
| Trial ID | NCT07428265 on ClinicalTrials.gov |
What this trial studies
This randomized interventional trial assigns adults with diabetic carbuncles to either cruciate incision and drainage or saucerization, with all participants receiving postoperative VAC therapy. Investigators will record intraoperative blood loss and measure time to complete wound healing, with wound assessments every 14 days until healed. Key exclusions include major comorbidities (CKD, CLD, CVA), wounds near the anal opening or joints, and inability to tolerate VAC. The goal is to determine which surgical approach, when combined with VAC, yields better perioperative and healing outcomes.
Who should consider this trial
Good fit: Adults aged 25–70 with diabetes and a carbuncle requiring surgical drainage, ASA class II–III, who can tolerate VAC and provide consent are ideal candidates.
Not a fit: Patients with significant comorbidities (CKD, CLD, CVA), wounds near the anal opening or joints, or those unable to tolerate VAC are unlikely to benefit from the trial interventions.
Why it matters
Potential benefit: If one technique shows less blood loss and faster wound closure, patients could experience fewer complications, shorter healing times, and reduced hospital care.
How similar studies have performed: VAC therapy is well established for promoting wound healing, but randomized head-to-head comparisons of cruciate incision versus saucerization specifically for diabetic carbuncles are limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients of either gender aged 25-70 years with ASA class 2-3 presenting to the emergency department with carbuncle requiring surgical drainage Exclusion Criteria: * Failure to tolerate VAC * Patient with co-morbidities like: CKD, CLD, CVA * Patients not giving consent * Close to the anal opening * Wound near the joint
Where this trial is running
Lahore, Punjab Province
- King Edward Medical University/Mayo Hospital Lahore — Lahore, Punjab Province, Pakistan (Recruiting)
Study contacts
- Study coordinator: Adnan Ali, MBBS
- Email: heartheart5000@gmail.com
- Phone: +92 334 4323941
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.