Creating lung organoids from human lung stem cells in COPD patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to proliferate human lung stem cells in vitro to establish lung organoids derived from patients with Chronic Obstructive Pulmonary Disease (COPD). Participants will undergo pulmonary bronchoscopy to collect samples necessary for organoid construction. The study seeks to determine the feasibility of human lung stem cell proliferation and the successful establishment of lung organoids from COPD patients. This approach could provide insights into the disease mechanisms and potential therapeutic avenues.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 1\. Age under 55, regardless of gender
* 2\. Patients with COPD lung disease who are going to undergo bronchoscopic biopsy
* 3\. No genetic diseases and other respiratory diseases

Exclusion Criteria:

* Other conditions determined by the investigators to be unsuitable for inclusion, such as difficult sampling, difficult follow-up, and complicated with other serious diseases

Where it's running

• China-Japan Friendship Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Mingming Deng, MD
• Email: isdeng1017@163.com
• Phone: +8618801336854

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.