Creating and testing a quality of life questionnaire for cardiac sarcoidosis patients

Development and Validation of a Health-related Quality of Life Tool for Patients With Cardiac Sarcoidosis

Observational Queen Mary University of London · NCT05145023

This study is trying to create and test a new questionnaire to help understand how cardiac sarcoidosis affects the daily lives of patients.

Quick facts

Study typeObservational
Enrollment120 (estimated)
Ages18 Years to 120 Years
SexAll
SponsorQueen Mary University of London Academic / other
Locations2 sites (Cambridge and 1 other locations)
Trial IDNCT05145023 on ClinicalTrials.gov

What this trial studies

This study aims to develop and validate a new questionnaire, the CARD-SARC, specifically designed to measure health-related quality of life in patients with cardiac sarcoidosis. It involves interviewing patients to understand the impact of their condition on daily life, followed by the creation of a draft questionnaire. The draft will then be tested for reliability and validity by having patients complete it alongside established quality of life measures. The study is conducted across two NHS specialist centers in the UK.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older with a confirmed diagnosis of cardiac sarcoidosis attending outpatient clinics at specialist centers.

Not a fit: Patients who are unable or unwilling to provide informed consent or complete the study questionnaires will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a reliable tool for assessing quality of life in cardiac sarcoidosis patients, leading to better patient care and management.

How similar studies have performed: While the approach of developing a specific quality of life tool for cardiac sarcoidosis is relatively novel, similar studies have successfully created and validated quality of life questionnaires for other chronic conditions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult (≥ 18 years)
* Patients with a probable (50-90% likelihood) or highly probable (\>90% likelihood) diagnosis of cardiac sarcoidosis (CS) by a multidisciplinary team meeting in a CS-specialist centre as per the WASOG criteria
* Patients attending outpatient clinics in a CS-specialist centre

Exclusion Criteria:

* Unable or unwilling to give informed consent
* Unable or unwilling to give and/or complete the study questionnaires • Inability to understand written and/or verbal English

Where this trial is running

Cambridge and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cardiac Sarcoidosiscardiac sarcoidosishealth-related quality of life
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.