Creating a registry to analyze the microbiome in patients with urologic cancers
Official title: Development of Urologic Registry for Personalized Medicine in Patients With Urologic Malignant Diseases by Analyzing Microbiome
Run by Yonsei University · NCT04625556 · Data updated 2026-11-12
This study is trying to create a database to see how the bacteria in our bodies might affect the diagnosis and treatment of urologic cancers like prostate and bladder cancer in Korean patients.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years and up |
| Sex | All |
| Enrollment | 3000 (estimated) |
| Sponsor | Yonsei University Academic / other |
| Locations | 1 site (Seoul) |
| Status | Recruiting |
| Started | December 19, 2022 |
| Main results expected | October 2030 |
| Study ends | October 2030 |
| Registry record updated | January 31, 2023 |
| Trial ID | NCT04625556 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients diagnosed with urological malignancies who have undergone surgery at Severance Hospital between October 2020 and October 2030.
✕Probably not a fit
Patients who do not agree to participate in the study or those who are considered vulnerable and unable to provide informed consent may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to develop a comprehensive registry focused on the microbiome's role in urological malignancies, including prostate, renal cell, bladder, and ureter cancers, within the Korean population. By analyzing microbiome samples from tissue, plasma, stool, and urine, the study seeks to enhance diagnosis, monitor disease progression, and evaluate therapeutic responses. The research will also build a large database to better understand the microbiome's impact on these cancers, addressing a significant gap in current knowledge.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic and monitoring tools for patients with urological malignancies.
How similar studies have gone: While there have been limited studies on the microbiome's role in urological malignancies, this approach is relatively novel and underexplored.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients diagnosed as urological malignancies (prostate cancer, renal cell cancer, bladder cancer, and ureter cancer) * Patients who have undergone surgeries due to urological malignancies in Severance Hospital, Sinchon from 2020.10 and 2030.10 * Those who agree to give permission to use their human source information * Those who agree with this study Exclusion Criteria: * Those who do not agree with this study * Vulnerable participants who are likely to be vulnerable to coercion or undue influence or lack decision-making
Where it's running
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Yonsei Severance Hospital
Seoul, South Korea Recruiting
Study contacts
- Principal investigator: Won Sik Ham — Severance Hospital
- Study coordinator: Won Sik Ham
- Email: uroham@yuhs.ac
- Phone: 82-02-2228-2310
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.