Creating a live biobank for breast cancer patients
De-convoluting Interactions Between Genes, the Cancer Environment, and the Immune System to Develop Therapies That Work for You
This study is trying to create a collection of living tumor samples from breast cancer patients to better understand their cancer and find personalized treatments.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 400 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | Female |
| Sponsor | Weill Medical College of Cornell University Academic / other |
| Locations | 2 sites (New York, New York and 1 other locations) |
| Trial ID | NCT05134779 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on breast cancer patients to build a live tissue biobank of Patient Derived Tumor Organoids (PDOs). Samples will be collected at critical points during the disease course, including during surgery and at recurrence or metastasis. The goal is to understand the interactions between genes, the cancer environment, and the immune system to develop personalized therapies. Blood samples will also be collected to complement the tumor tissue data.
Who should consider this trial
Good fit: Ideal candidates for this study are patients with a historically proven diagnosis of breast cancer.
Not a fit: Patients with other cancers in addition to breast cancer will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more effective, personalized treatments for breast cancer patients.
How similar studies have performed: Other studies utilizing biobanks and patient-derived organoids have shown promise in advancing personalized cancer therapies, indicating a potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients will historically proven BC are eligible to be on the study Exclusion Criteria: * Carriers of other cancers other than breast.
Where this trial is running
New York, New York and 1 other locations
- Brooklyn Methodist Hospital - NewYork Presbyterian — New York, New York, United States (Recruiting)
- New York Presbyterian Hospital - Queens — New York, New York, United States (Recruiting)
Study contacts
- Principal investigator: Silvia Formenti, M.D. — Weill Medical College of Cornell University
- Study coordinator: Fabiana Gregucci, M.D.
- Email: fgr4002@med.cornell.edu
- Phone: 646-962-3110
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.