Clinical trial Recruiting at 2 sites Observational Ages 18 to 90 Women only

Creating a live biobank for breast cancer patients

Official title: De-convoluting Interactions Between Genes, the Cancer Environment, and the Immune System to Develop Therapies That Work for You

Run by Weill Medical College of Cornell University · NCT05134779 · Data updated 2026-11-12

This study is trying to create a collection of living tumor samples from breast cancer patients to better understand their cancer and find personalized treatments.

Quick facts

Study typeObservational
Ages18 Years to 90 Years
SexWomen only
Enrollment400 (estimated)
SponsorWeill Medical College of Cornell University
Academic / other
Locations2 sites (New York, New York and 1 other locations)
StatusRecruiting
StartedJanuary 12, 2022
Main results expectedDecember 31, 2027
Study endsDecember 31, 2028
Registry record updatedDecember 18, 2025
Trial IDNCT05134779 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients with a historically proven diagnosis of breast cancer.

Probably not a fit

Patients with other cancers in addition to breast cancer will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on breast cancer patients to build a live tissue biobank of Patient Derived Tumor Organoids (PDOs). Samples will be collected at critical points during the disease course, including during surgery and at recurrence or metastasis. The goal is to understand the interactions between genes, the cancer environment, and the immune system to develop personalized therapies. Blood samples will also be collected to complement the tumor tissue data.

Why it matters

Potential benefit: If successful, this study could lead to more effective, personalized treatments for breast cancer patients.

How similar studies have gone: Other studies utilizing biobanks and patient-derived organoids have shown promise in advancing personalized cancer therapies, indicating a potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients will historically proven BC are eligible to be on the study

Exclusion Criteria:

* Carriers of other cancers other than breast.

Where it's running

  • Brooklyn Methodist Hospital - NewYork Presbyterian
    New York, New York, United States
    Recruiting
  • New York Presbyterian Hospital - Queens
    New York, New York, United States
    Recruiting

Study contacts

  • Principal investigator: Silvia Formenti, M.D. — Weill Medical College of Cornell University
  • Study coordinator: Fabiana Gregucci, M.D.
  • Email: fgr4002@med.cornell.edu
  • Phone: 646-962-3110

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.