Creating a large database of cardiovascular patients

Cardiology Biobank Registry

Observational Emory University · NCT00378924

This study is creating a large database of around 12,000 people with heart problems to help understand what causes these issues and how to treat them better.

Quick facts

Study typeObservational
Enrollment12000 (estimated)
Ages20 Years and up
SexAll
SponsorEmory University Academic / other
Locations1 site (Atlanta, Georgia)
Trial IDNCT00378924 on ClinicalTrials.gov

What this trial studies

This study aims to establish a comprehensive database of approximately 12,000 patients with cardiovascular diseases, including those undergoing cardiac catheterization and heart failure treatment. Data will be collected from various locations in the Atlanta metropolitan area, including hospitals, community events, and clinics. The collected data will encompass medical records, patient questionnaires, DNA samples, and non-invasive measurements to better understand the causes and treatment of cardiovascular diseases. Statistical analyses will be conducted to identify factors influencing conditions such as coronary heart disease, heart failure, and hypertension.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older with active cardiovascular diseases or those in satisfactory health residing in the Atlanta metropolitan area.

Not a fit: Patients with significant anemia, active cancer, or those unable to provide consent may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and treatment of cardiovascular diseases, ultimately benefiting patients with these conditions.

How similar studies have performed: Other studies have successfully established similar databases, contributing valuable insights into cardiovascular diseases.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. All hospital and clinic patients aged 18 years and older
2. Patients with active cardiovascular disease including but not limited to

   1. Ischemic Heart Disease
   2. Heart Failure and Cardiomyopathies
   3. Peripheral Vascular Disease
   4. Valve disease
   5. Adult Congenital Heart disease
   6. Electrophysiological Disorders
3. Any Atlanta metropolitan area resident aged 18 and above in satisfactory physical health and able to tolerate a blood draw or buccal swab.

Exclusion Criteria:

1. Significant Documented Anemia (Hemoglobin \<8 g/dL)
2. Blood transfusions within past 3 weeks
3. Active Cancer (non-skin cancers)
4. Enrollment against doctor recommendation
5. Patient not able to provide consent including but not limited to:

   1. Intubated and critically unwell patients
   2. Dementia
   3. Alzheimer's disease
   4. Moderate to severe alcohol or drug abuse
   5. Against religious beliefs (e.g. Jehovah's witness

Where this trial is running

Atlanta, Georgia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cardiovascular Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.