Creating a decision aid tool for women with small, asymptomatic uterine leiomyomas

Establishment of a Decision Aid Tool for Asymptomatic Small Leiomyoma and Analysis of Influencing Factors for Clinical Decision-making Using HIFU

Observational Shenzhen Maternity & Child Healthcare Hospital · NCT05500118

This study is trying to create a helpful tool for women with small, non-problematic uterine fibroids to make better decisions about their health.

Quick facts

Study typeObservational
Enrollment120 (estimated)
Ages18 Years to 55 Years
SexFemale
SponsorShenzhen Maternity & Child Healthcare Hospital Academic / other
Locations1 site (Shenzhen, Guangdong)
Trial IDNCT05500118 on ClinicalTrials.gov

What this trial studies

This observational study aims to develop a decision aid tool for women diagnosed with asymptomatic small leiomyomas, focusing on improving clinical decision-making. A committee of designers, doctors, nurses, and patients will collaborate to identify factors influencing these decisions based on clinical guidelines and evidence-based medicine. The study will involve prospective trials to assess whether the decision aid tool enhances patients' decision-making efficacy and improves their reported outcomes. Participants will be women aged 18-55 with specific criteria regarding their leiomyoma diagnosis.

Who should consider this trial

Good fit: Ideal candidates are women aged 18-55 with asymptomatic small leiomyomas diagnosed via imaging.

Not a fit: Patients with symptomatic leiomyomas, those who have undergone myomectomy, or have other significant gynecological conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this tool could empower patients to make more informed decisions regarding their treatment options for asymptomatic leiomyomas.

How similar studies have performed: While similar decision aid tools have been explored in other contexts, this specific approach for asymptomatic leiomyomas is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Diagnosis of leiomyoma: patients with leiomyoma diagnosed by imaging examinations (ultrasound and MRI) have no clinical symptoms;
2. Female with age in 18-55 years old;
3. The maximum diameter of a single leiomyoma is less than 5m, and the number does not exceed 10 by MRI;
4. No contraindications for sedation and analgesia;
5. Patients and their families agree to join this study, and can follow up on time.

Exclusion Criteria:

1. History of myomectomy, including transabdominal, laparoscopic, hysteroscopy, etc.;
2. History of connective tissue diseases or radiotherapy, especially abdominal radiotherapy;
3. With pregnancy, acute inflammation of the reproductive tract, or other gynecological benign and malignant diseases such as endometriosis and ovarian tumors;
4. The maximum diameter of leiomyoma is greater than or equal to 5cm;
5. Suspected malignant tumor, such as sarcoma;
6. Those with language communication barriers and unable to cooperate with sedative and analgesic programs;
7. Abdominal scarring, when diagnosed by ultrasound transabdominal scan, has obvious sound attenuation (more than 10mm range).

Where this trial is running

Shenzhen, Guangdong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Leiomyoma, UterineHigh-Intensity Focused Ultrasound AblationPatients Decision Aids
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.