Creating a database of full body radiographs in healthy volunteers
Official title: Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers
Run by University of Colorado, Denver · NCT03076658 · Data updated 2026-11-12
This study is trying to create a database of full body x-rays from healthy people to help doctors understand normal bone structure and improve treatment for spine issues.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 21 Years to 85 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | University of Colorado, Denver Academic / other |
| Locations | 1 site (Aurora, Colorado) |
| Status | Recruiting |
| Started | September 2016 |
| Main results expected | January 2031 |
| Study ends | January 2031 |
| Registry record updated | September 28, 2023 |
| Trial ID | NCT03076658 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are healthy males and females aged 21 to 85 without a history of spine surgery or significant skeletal disorders.
✕Probably not a fit
Patients with a history of spine surgery, severe osteoarthritis, or other significant medical conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the skeletal structure of healthy individuals by analyzing full body radiographs taken at 10-year intervals. Using a low dose x-ray system called EOS, the researchers will collect images from 25 male and 25 female volunteers per decade, ranging from ages 21 to 85. The goal is to establish a baseline of 'normal' skeletal parameters that can inform clinical decision-making and surgical planning for spine-related conditions. The resulting open access database will serve as a valuable resource for both spine surgeons and researchers.
Why it matters
Potential benefit: If successful, this study could provide critical normative data that enhances the understanding of skeletal changes with age, improving patient outcomes in spine surgery.
How similar studies have gone: While the approach of creating a normative database is established, the use of the EOS imaging system for this specific purpose is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Males and females age 21-85 without a history of spine surgery. Exclusion Criteria: * History of spine or neural axis surgery * History of cancer with or without metastatic disease * Connective tissue, rheumatologic (or other inflammatory arthropathies), or neurologic disorders * History of knee replacement surgery, as these may have contractures causing unexpected changes in alignment * Severe osteoarthritis of the hips/knees/ankles * Spondylitis * Compression fractures or other trauma of the spinal column * Previous trauma/fractures of the pelvis whether or not surgery was required * Previous trauma or fractures of the lower extremities requiring surgery * Pregnant women * BMI \>37 * Oswestry Disability Index score \>25
Where it's running
-
University of Coloardo Denver
Aurora, Colorado, United States Recruiting
Study contacts
- Principal investigator: Christopher Kleck, MD — University of Colorado, Denver
- Study coordinator: David Calabrese
- Email: david.calabrese@ucdenver.edu
- Phone: 303-524-2550
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.