Creating a database for tracking drug-resistant bacterial infections in Switzerland

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to develop a shared surveillance database that connects human and veterinary microbiology laboratories in Switzerland. The database will facilitate near real-time molecular epidemiology, allowing for effective tracking of hypervirulent and multidrug-resistant bacterial pathogens. By analyzing previously collected genomic and epidemiological data, the study seeks to enhance outbreak recognition and transmission monitoring across different environments, including humans, animals, and the environment. The focus is on improving public health responses to significant bacterial infections.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All patients with either colonisations or infections with either a bacterial or a viral pathogen, where whole genome sequencing data and available minimal epidemiological, demographic and clinical data
* Pathogens included into analysis are: Multidrug-resistant bacteria include: methicillin resistant Staphylococcus aureus (MRSA), Carbapenemase- and/or extended spectrum betalactamase (ESBL)-producing Enterobacteriaceae and non-fermenting bacteria including Pseudomonas aeruginosa and Acinetobacter baumannii, Vancomycin resistant Enterococcus faecium, and others; virulent bacteria include: Neisseria meningitidis, Neisseria gonorrhoeae, Mycobacterium tuberculosis, Campylobacter spp., Salmonella spp., Legionella pneumophila, Listeria monocytogenes, and Streptococcus pneumoniae, and others; Viruses include: Influenza viruses, Measles virus, Enterovirus E68, Respiratory Syncytial Virus and others.

Exclusion Criteria:

* Decline to sign a general consent or any other declining statement against using data for research purposes.

Where it's running

• University Hospital Basel
  Basel, Switzerland Recruiting
• University of Bern
  Bern, Switzerland Recruiting
• University Hospital Geneva
  Geneva, Switzerland Recruiting
• University Hospital Lausanne CHUV
  Lausanne, Switzerland Recruiting
• University of Zurich
  Zurich, Switzerland Recruiting

Study contacts

• Principal investigator: Hans Hirsch, Prof. Dr. — Biozentrum, University of Basel
• Study coordinator: Hans Hirsch, Prof. Dr.
• Email: hans.hirsch@unibas.ch
• Phone: +41 61 32 86697

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.