Creating a database for patients with thrombotic microangiopathies

Construction of a Database for Thrombotic Microangiopathy

Observational The First Affiliated Hospital of Soochow University · NCT05634928

This study is creating a detailed database to collect important information about patients with thrombotic microangiopathies to help improve understanding and treatment of the condition.

Quick facts

Study typeObservational
Enrollment500 (estimated)
SexAll
SponsorThe First Affiliated Hospital of Soochow University Academic / other
Locations1 site (Suzhou, Jiangsu)
Trial IDNCT05634928 on ClinicalTrials.gov

What this trial studies

This observational study aims to construct a comprehensive database for patients diagnosed with thrombotic microangiopathies by collecting detailed clinical data. Patient information will be gathered through the Hitech case system and follow-up via telephone and outpatient visits. The study will include approximately 200 cases and will take place at the First Affiliated Hospital of Soochow University from December 2022 to November 2027, focusing on key clinical indicators such as age, gender, and specific laboratory findings related to the condition.

Who should consider this trial

Good fit: Ideal candidates for this study are patients exhibiting specific laboratory criteria indicative of thrombotic microangiopathies.

Not a fit: Patients who are unable or unwilling to cooperate with the study procedures will not benefit from this study.

Why it matters

Potential benefit: If successful, this database could enhance understanding and management of thrombotic microangiopathies, leading to improved patient outcomes.

How similar studies have performed: While this approach is observational and data-driven, similar studies have successfully utilized patient databases to improve understanding of complex conditions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* The patient has elevated lactate dehydrogenase to more than twice the baseline value, platelets less than 20 or decreased by more than 50% within 24 hours, and more than 2% of schistocytes visible on a peripheral blood smear. Alternatively, pathological sections show extensive micro thrombosis.

Exclusion Criteria:

* The investigator considers the subject unable or unwilling to cooperate with the study procedures.

Where this trial is running

Suzhou, Jiangsu

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Thrombotic Microangiopathies
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.