Creating a computer simulation to improve treatment for bloodstream infections and sepsis
Computer Simulation Model of Patients With Bloodstream Infection, Sepsis and Systemic Infection (CSM-BSI)
Liverpool University Hospitals NHS Foundation Trust · NCT06271031
This study is trying to create a computer model to help doctors find better ways to treat bloodstream infections and sepsis while avoiding unnecessary use of antibiotics.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Liverpool University Hospitals NHS Foundation Trust (other gov) |
| Locations | 1 site (Liverpool) |
| Trial ID | NCT06271031 on ClinicalTrials.gov |
What this trial studies
This study aims to develop a computer simulation model to analyze the treatment pathways for patients with bloodstream infections, sepsis, and systemic infections. It involves conducting interviews with healthcare staff to map patient care processes and analyzing historical data on infections and antibiotic treatments. The simulation will help healthcare decision-makers understand the impact of policy changes and resource allocation on patient outcomes, particularly in avoiding antibiotic overuse. The observational phase will last for 30 days, focusing on real-time patient treatment observations.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older who are being treated for bloodstream infections in Liverpool University Hospitals.
Not a fit: Patients under 18 years old or those not managed on an acute hospital site will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies for patients with bloodstream infections, ultimately reducing mortality and antibiotic resistance.
How similar studies have performed: While similar approaches have been explored, this specific simulation model for bloodstream infections and sepsis is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Sub-study 2 (retrospective data collection) * Patients who were managed within a LUFT acute hospital site (Aintree or Royal) and had a concurrent blood culture investigation requested * Age ≥ 18 years at the time of the study. Sub-study 3 (observational study) * Patients with blood culture investigation requested during the observation period, and staff caring for the patients. Exclusion Criteria: * Age \< 18 years at the time of the study * Blood culture requested but patient not managed on an acute hospital site.
Where this trial is running
Liverpool
- Liverpool University Hospitals Foundation Trust — Liverpool, United Kingdom (RECRUITING)
Study contacts
- Principal investigator: Alessandro D Gerada — University of Liverpool
- Study coordinator: Esha D Sheth
- Email: e.d.m.sheth@liverpool.ac.uk
- Phone: 07864026738
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Sepsis, Bloodstream Infection, Bacteraemia