Creating a clinical database and biobank for schizophrenia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter observational study aims to establish a comprehensive cohort of patients with schizophrenia across various age groups and disease stages. Participants will undergo standardized diagnostic assessments and regular follow-ups for at least one year, during which extensive clinical data will be collected. The study will utilize a multidimensional assessment framework to investigate the etiology, disease progression, and clinical outcomes of schizophrenia. Additionally, blood samples will be collected for biomarker exploration, contributing to early diagnosis and improved treatment strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 1.Clinical diagnosis of schizophrenia according to ICD-11.
* 2.Confirmation of the diagnosis of schizophrenia using the SCID-5-RV (DSM-5 Structured Clinical Interview for DSM-5 Disorders - Research Version).

Exclusion criteria:

* 1.Clinical diagnosis or SCID-5-RV assessment confirming neurodevelopmental disorders, bipolar and related disorders, substance use disorders (excluding alcohol and tobacco).
* 2.Presence of severe or acute physical illnesses, including traumatic brain injury, intracranial space-occupying or infectious diseases, acute cardiovascular diseases, acute respiratory system diseases, acute hematological disorders, etc.
* 3.Presence of clearly defined genetic diseases, including tuberous sclerosis, multiple sclerosis, Kleefstra syndrome, 22q11.2 deletion syndrome, Prader-Willi syndrome, Klinefelter syndrome (47,XXY), etc.

Where it's running

• Mental Health Institute of Second Xiangya Hospital,CSU
  Changsha, Hunan, China Recruiting
• Anhui Mental Health Center
  Hefei, Anhui, China Active not recruiting
• The First Affiliated Hospital of Zhengzhou University
  Zhengzhou, Henan, China Active not recruiting
• Nanjing Brain Hospital, Nanjing Medical University
  Nanjing, Jiangsu, China Active not recruiting

Study contacts

• Study coordinator: Renrong Wu, M.D., Ph.D.
• Email: wurenrong2013@163.com
• Phone: 15874179855

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Quality of life and safety in quetiapine use for schizophrenia or bipolar disorder

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• Neuronavigated rTMS for treatment-resistant auditory hallucinations

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.