Clinical trial No longer in our active list Interventional Ages 18 to 45

Creating 3D Models of the Knee from MRI for ACL Tear Diagnosis

Official title: Comparison of a 3D Reconstruction of the Knee Based on MRI With a 3D Reconstruction of the Knee Based on Scanner - Exploratory Study

Run by GCS Ramsay Santé pour l'Enseignement et la Recherche · NCT05912777 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing if creating 3D models of the knee from MRI scans can help doctors better diagnose and plan treatment for athletes with ACL tears.

More ACL Tear trials

Quick facts

Study typeInterventional
Ages18 Years to 45 Years
SexAll
Enrollment50 (estimated)
SponsorGCS Ramsay Santé pour l'Enseignement et la Recherche
Academic / other
Locations1 site (Lyon)
Trial IDNCT05912777 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are French-speaking individuals aged 18 to 45 who are eligible for ACL reconstruction and have had an MRI performed at the designated orthopedic center.

Probably not a fit

Patients with prior surgeries on the affected knee or those with multi-ligament injuries may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on patients with anterior cruciate ligament (ACL) tears, a common injury among athletes. It aims to utilize MRI imaging to create accurate 3D models of the knee, which can assist in both preoperative planning and postoperative evaluation. By avoiding the use of irradiating imaging techniques, this approach seeks to enhance the visualization of anatomical structures that are not easily seen in traditional scans. The study will assess the geometric precision and reproducibility of these 3D reconstructions derived from MRI.

Why it matters

Potential benefit: If successful, this method could improve surgical planning and outcomes for patients with ACL tears by providing detailed anatomical models without radiation exposure.

How similar studies have gone: While the use of MRI for ACL diagnosis is established, the specific approach of creating 3D models from MRI data is relatively novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient, male or female, aged between ≥ 18 and ≤ 45 years old
* Patient eligible for ACL reconstruction
* Patient with an MRI performed at the SANTY orthopedic center or according to the protocol defined by the radiologists of the orthopedic center SANTY
* Patient with an MRI performed ≥ 3 weeks after ACL tear
* Affiliated patient or beneficiary of a social security scheme
* French-speaking patient who signed an informed consent

Exclusion Criteria:

* Patient with a surgical history on the affected knee
* Patient with a multi-ligament lesion
* Patient already included in another study
* Protected patient: adult under guardianship, curatorship or other protection legal, deprived of liberty by judicial or administrative decision
* Patient hospitalized without consent

Where it's running

  • Hôpital Privé Jean Mermoz
    Lyon, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Quadriceps strengthening after ACL reconstruction in adolescents

    This project will test whether adding neuromuscular electrical stimulation (NMES) and blood flow restriction (BFR) training to standard physical therapy improves knee strength and movement in adolescents after ACL reconstruction.

    Recruiting Stanford University · Sunnyvale, California · NCT07015541

  • Assessing soleus muscle strength in patients with ACL tears

    This study is testing the strength of a muscle in the calf of people with ACL tears to see how it compares to their uninjured leg and to healthy volunteers.

    Recruiting University of Liverpool · Liverpool · NCT06235736

  • Using metformin to reduce knee pain after ACL surgery

    This study is testing if metformin can help reduce knee pain and prevent arthritis in people recovering from ACL surgery.

    Recruiting at 9 sites Phase 2 Brigham and Women's Hospital · Atlanta, Georgia and 8 other locations · NCT06096259

  • Evaluating ACL and ALL Reconstruction in Children

    This study is testing if kids who have surgery for a knee ligament injury do better when they have two ligaments fixed instead of just one.

    Recruiting Ann & Robert H Lurie Children's Hospital of Chicago · Chicago, Illinois · NCT04825587

  • Accelerated MRI techniques for assessing cartilage health

    This study is testing new, faster MRI methods to see if they can help people at risk for osteoarthritis by checking the health of their cartilage more accurately.

    Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT04536103

  • Arthrocentesis with ACL Reconstruction for Acute ACL Tears

    This trial tests whether draining the knee before and after ACL reconstruction helps reduce inflammation, prevent muscle loss, and speed recovery in people with a recent ACL tear.

    Recruiting at 2 sites Ohio State University · Columbus, Ohio and 1 other locations · NCT07929922

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.