Creatine taken before sleep improves exercise performance in active women

Pre-Sleep Creatine Enhances Anaerobic Power in Recreationally Active Females

Not applicable Interventional Ankara Yildirim Beyazıt University · NCT06937190

This study tests if taking creatine before bed can help active women perform better in workouts and recover faster.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment24 (estimated)
Ages18 Years to 25 Years
SexFemale
SponsorAnkara Yildirim Beyazıt University Academic / other
Locations1 site (Shabestar, East Azerbaijan Province)
Trial IDNCT06937190 on ClinicalTrials.gov

What this trial studies

This study examines the effects of taking creatine monohydrate before sleep on anaerobic performance and muscle recovery in recreationally active females. Participants will be randomly assigned to receive either creatine or a placebo for seven days, with performance assessed through the Wingate Anaerobic Test. Blood samples will be collected to analyze muscle damage markers before and after the supplementation period. The goal is to determine if pre-sleep creatine can enhance performance and recovery in this population.

Who should consider this trial

Good fit: Ideal candidates are females aged 18 to 25 who are recreationally active and engage in structured resistance training.

Not a fit: Patients with recent musculoskeletal injuries or those using performance-enhancing substances may not benefit from this study.

Why it matters

Potential benefit: If successful, this could lead to improved exercise performance and recovery strategies for recreationally active women.

How similar studies have performed: While there have been studies on creatine supplementation, this specific approach of pre-sleep administration in recreationally active females is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Female, aged 18 to 25 years

Recreationally active (engaging in structured resistance training 3-4 times per week for the past 6 months)

Regular menstrual cycles (used for scheduling purposes)

Able and willing to provide informed consent

Agreement to maintain normal diet and training routines throughout the study

Exclusion Criteria:

History of musculoskeletal injury affecting lower or upper limbs within the past 6 months

Known allergy or intolerance to creatine or maltodextrin

Use of performance-enhancing substances or supplements within the last 30 days

Use of recovery modalities such as massage, cryotherapy, or compression garments during the study period

Current use of anti-inflammatory medication

Pregnancy or breastfeeding

Inability to comply with study protocol or scheduled assessments

Where this trial is running

Shabestar, East Azerbaijan Province

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Anaerobic PerformanceSports NutritionExercise RecoveryMuscle FatigueCreatine SupplementationRecreational Physical ActivityFemale AthletesCreatine Monohydrate
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.