Clinical trial Recruiting at 1 site Interventional Ages 18 to 25 Women only

Creatine taken before sleep improves exercise performance in active women

Official title: Pre-Sleep Creatine Enhances Anaerobic Power in Recreationally Active Females

Run by Ankara Yildirim Beyazıt University · NCT06937190 · Data updated 2026-11-12

This study tests if taking creatine before bed can help active women perform better in workouts and recover faster.

Quick facts

Study typeInterventional
Ages18 Years to 25 Years
SexWomen only
Enrollment24 (estimated)
SponsorAnkara Yildirim Beyazıt University
Academic / other
Locations1 site (Shabestar, East Azerbaijan Province)
StatusRecruiting
StartedApril 1, 2025
Main results expectedMay 10, 2025
Study endsJuly 10, 2025
Registry record updatedApril 22, 2025
Trial IDNCT06937190 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are females aged 18 to 25 who are recreationally active and engage in structured resistance training.

Probably not a fit

Patients with recent musculoskeletal injuries or those using performance-enhancing substances may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study examines the effects of taking creatine monohydrate before sleep on anaerobic performance and muscle recovery in recreationally active females. Participants will be randomly assigned to receive either creatine or a placebo for seven days, with performance assessed through the Wingate Anaerobic Test. Blood samples will be collected to analyze muscle damage markers before and after the supplementation period. The goal is to determine if pre-sleep creatine can enhance performance and recovery in this population.

Why it matters

Potential benefit: If successful, this could lead to improved exercise performance and recovery strategies for recreationally active women.

How similar studies have gone: While there have been studies on creatine supplementation, this specific approach of pre-sleep administration in recreationally active females is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Female, aged 18 to 25 years

Recreationally active (engaging in structured resistance training 3-4 times per week for the past 6 months)

Regular menstrual cycles (used for scheduling purposes)

Able and willing to provide informed consent

Agreement to maintain normal diet and training routines throughout the study

Exclusion Criteria:

History of musculoskeletal injury affecting lower or upper limbs within the past 6 months

Known allergy or intolerance to creatine or maltodextrin

Use of performance-enhancing substances or supplements within the last 30 days

Use of recovery modalities such as massage, cryotherapy, or compression garments during the study period

Current use of anti-inflammatory medication

Pregnancy or breastfeeding

Inability to comply with study protocol or scheduled assessments

Where it's running

  • Islamic Azad University, Shabestar Branch
    Shabestar, East Azerbaijan Province, Iran
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.