Cranberry phospholipids to reduce daytime urination in healthy Japanese adults
Official title: Effects of the Consumption of Test Product on Urination in Healthy Japanese Adults: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Comparison Trial
Run by Indena S.p.A · NCT07393126 · Data updated 2026-11-12
This test will see if taking two cranberry phospholipid tablets daily for eight weeks reduces daytime urination in healthy Japanese adults who feel they urinate too often.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 76 (estimated) |
| Sponsor | Indena S.p.A Industry-sponsored |
| Locations | 2 sites (Nerima-ku, Tokyo and 1 other locations) |
| Status | Recruiting |
| Started | December 8, 2025 |
| Main results expected | March 30, 2027 |
| Study ends | April 30, 2027 |
| Registry record updated | September 30, 2026 |
| Trial ID | NCT07393126 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Healthy Japanese adults who report high bother from daytime urinary frequency, have relatively low baseline OABSS urgency scores, and have positive urine leukocytes at baseline are the intended candidates.
✕Probably not a fit
People with chronic medical conditions, those on treatments for cardiac, hepatic, renal, or metabolic diseases, those with more severe OAB symptoms, or those with implanted cardiac devices are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults who report bothersome daytime urinary frequency will be assigned to receive either cranberry phospholipid tablets or a matching placebo and will take two tablets daily for eight weeks. Participants will complete questionnaires on overactive bladder symptoms (OABSS), OAB-specific quality of life (OAB-q), and urinary frequency during the study period. Researchers will compare changes in daytime urinary frequency between the cranberry phospholipid and placebo groups. The trial enrolls healthy Japanese men and women who meet specific baseline symptom and urine test criteria.
Why it matters
Potential benefit: If successful, this could offer a low-risk supplement option to reduce bothersome daytime urinary frequency.
How similar studies have gone: Traditional cranberry extracts have shown mixed results for urinary symptoms and UTI prevention, and cranberry phospholipids are a newer formulation with limited prior clinical data.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Japanese * Men or women * Adults * Healthy individuals * Individuals with positive urine leukocytes at baseline * Individuals whose score of urinary urgency of overactive bladder symptom score (OABSS) is less than two or total score of OABSS is less than three at baseline * Individuals whose "frequent urination during the daytime hours" of "symptom bother" of OAB-q is relatively high at baseline Exclusion Criteria: * Individuals undergoing medical treatment or having a medical history of malignant tumor, heart failure, or myocardial infarction * Individuals carrying a pacemaker or an implantable cardioverter defibrillator * Individuals undergoing treatment for any of the following chronic diseases: cardiac arrhythmia, liver disease, kidney disease, cerebrovascular disorder, rheumatism, diabetes mellitus, dyslipidemia, hypertension, or any other chronic diseases * Individuals who use or take "Foods for Specified Health Uses", "Foods with Functional Claims", or other functional food/beverage as part of their daily diet * Individuals currently regularly taking medications (including herbal medicines) and supplements * Individuals who are allergic to medicines and/or the test-product-related products in this trial * Individuals with urinary pain * Individuals undergoing treatment, have had treatment within two months, or need the treatment for diseases related to urination, e.g. benign prostatic hypertrophy, prostatitis, prostate cancer, overactive bladder, hypoactive bladder, cystitis, interstitial cystitis, bladder cancer, bladder stones, urethritis, urethral stricture, neurological disease, polyuria, and nocturnal polyuria * Individuals have overactive bladder symptom (individuals who urinate eight times or more per day, and have urinary urgency at least once a week) * Individuals wake up twice or more to urinate at bedtime * Individuals are pregnant, breast-feeding, and planning to become pregnant * Individuals have been enrolled in other clinical trials within the last 28 days before the agreement to participate in this trial or plan to participate another trial during this trial * Individuals are judged as ineligible to participate in the trial by the physician
Where it's running
-
Nerima Medical Association Minami-machi Clinic
Nerima-ku, Tokyo, Japan Recruiting -
Medical Corporation Seishinkai, Takara Clinic
Shinagawa-Ku, Tokyo, Japan Recruiting
Study contacts
- Study coordinator: Naoko Suzuki
- Email: group_gakujutsu@orthomedico.jp
- Phone: +81-3-3818-0610
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Community spread of multiple infectious diseases in Cambodia from a One Health perspective
This project will test how common and connected dengue, chikungunya, Zika, Japanese encephalitis, and West Nile infections are among people, animals, and the environment across Cambodia.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.