CPAP pressure equations versus sleep‑lab manual titration in Thai adults with obstructive sleep apnea
Official title: Comparative Study of CPAP Predictive Equations and In-laboratory Manual Titration in Thai Patients With Obstructive Sleep Apnea
Run by Thammasat University · NCT07376343 · Data updated 2026-11-12
This project will test whether CPAP predictive equations can match in‑lab manual titration for finding the right CPAP pressure in Thai adults with suspected obstructive sleep apnea.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | Thammasat University Academic / other |
| Locations | 2 sites (Pathum Thani and 1 other locations) |
| Status | Recruiting |
| Started | February 1, 2026 |
| Main results expected | October 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | April 17, 2026 |
| Trial ID | NCT07376343 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) in Thailand with suspected OSA who are scheduled for an in‑laboratory CPAP manual titration are the intended participants.
✕Probably not a fit
Patients who do not require in‑lab manual CPAP titration or whose optimal pressure cannot be determined during the night are unlikely to benefit from the findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This cross‑sectional observational study will enroll Thai patients aged 18 and older who are undergoing an in‑laboratory sleep study for suspected obstructive sleep apnea. During the overnight test, sleep technicians will record the optimal CPAP pressure determined by standard manual titration and will also calculate pressures using several published predictive equations. The predicted pressures will be compared to the manual titration results to identify which equation best matches the in‑lab standard in this Thai population. No experimental treatments are given; the protocol uses routine diagnostic testing and mathematical comparison of results.
Why it matters
Potential benefit: If an equation reliably predicts optimal CPAP pressure, patients could start effective CPAP therapy sooner and reduce the need for time‑consuming in‑lab titration.
How similar studies have gone: Published work has produced several CPAP predictive equations with mixed accuracy across populations, so while some equations matched manual titration in other cohorts, results vary and local validation is limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Suspected OSA * Undergoing an in-laboratory sleep study Exclusion Criteria: * No indication for in-laboratory manual CPAP titration * Failure to determine an optimal CPAP pressure during in-laboratory manual CPAP titration
Where it's running
-
Faculty of Medicine, Thammasat University
Pathum Thani, Thailand Recruiting -
Narongkorn Saiphoklang
Pathum Thani, Thailand Recruiting
Study contacts
- Principal investigator: Narongkorn Saiphoklang — Thammasat University Faculty of Medicine
- Study coordinator: Narongkorn Saiphoklang, MD
- Email: M_narongkorn@hotmail.com
- Phone: +6629269794
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.