Clinical trial Recruiting at 1 site Observational Ages 5 to 70

COVID-19 antibody and PCR testing program

Official title: Serological and PCR Testing for SARS-CoV-2. A Prospective Study Assessing Infection, Immunity, and Asymptomatic Carriage of COVID-19

Run by Richmond Pharmacology Limited · NCT04404062 · Data updated 2026-11-12

This project uses PCR and blood antibody tests to find current or past COVID-19 infection in people aged 5 to 70, including those with and without symptoms.

Quick facts

Study typeObservational
Ages5 Years to 70 Years
SexAll
Enrollment2500 (estimated)
SponsorRichmond Pharmacology Limited
Industry-sponsored
Locations1 site (London, London)
StatusRecruiting
StartedMarch 16, 2020
Main results expectedDecember 1, 2028
Study endsDecember 2028
Registry record updatedJune 17, 2026
Trial IDNCT04404062 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are people aged 5 to 70 who can attend the London site and are willing to provide blood and swab samples and comply with follow-up visits.

Probably not a fit

People outside the 5–70 age range or those seeking experimental treatments rather than diagnostic information are unlikely to receive direct clinical benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The program combines membrane-based immunoassays, quantitative IgG/IgM antibody measurements, and PCR testing on blood and respiratory samples to identify active infection and past exposure. Participants are screened longitudinally so antibody levels and PCR status can be tracked over time to estimate duration of immune response and asymptomatic carriage. Tests are applied to workers and their families, including children, with in-house PCR methods verified by an independent laboratory. Data will be used to support early detection of new infection waves and to help develop a quantitative laboratory reference for SARS-CoV-2 antibodies.

Why it matters

Potential benefit: If successful, the testing could help identify who is currently infectious or has developed antibodies, aiding infection-control decisions and monitoring vaccine responses.

How similar studies have gone: PCR and serology approaches are widely used and have reliably detected active infections and prior exposure, although quantitative antibody reference methods are still being refined.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male or female aged 5 to 70 years.
* An understanding, ability, and willingness to fully comply with the project procedures and restrictions.

Exclusion Criteria:

* Not applicable.

Where it's running

  • Richmond Pharmacology Ltd. 1a Newcomen St, London Bridge
    London, London, United Kingdom
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.