Couple-based intervention to improve quality of life for HIV male serodiscordant couples

Pilot Randomized Controlled Trial of Couple-based Intervention on Relationship Satisfaction and Quality of Life in HIV Male Serodiscordant Couples

Not applicable Interventional City University of Hong Kong · NCT06497751

This study is testing a new program to see if it can help improve the quality of life and relationship satisfaction for male couples in China where one partner is HIV positive and the other is not.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
Ages18 Years and up
SexMale
SponsorCity University of Hong Kong Academic / other
Locations4 sites (Chengdu and 3 other locations)
Trial IDNCT06497751 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of a couple-based intervention designed to enhance the quality of life and relationship satisfaction among HIV male serodiscordant couples in China. Participants will be randomly assigned to either the intervention group, which will receive three sessions of dyadic coping strategies, or the control group, which will receive usual care. The study aims to provide preliminary evidence on the intervention's efficacy while also assessing its feasibility and acceptability among participants.

Who should consider this trial

Good fit: Ideal candidates for this study are male couples where one partner is HIV positive and the other is HIV negative, both over the age of 18 and in a committed relationship for at least three months.

Not a fit: Patients who may not benefit from this study include those with low education levels, physical or psychological constraints that prevent assessment, or those diagnosed with other life-threatening diseases.

Why it matters

Potential benefit: If successful, this intervention could significantly improve the quality of life and relationship satisfaction for HIV serodiscordant couples.

How similar studies have performed: Other studies have shown promise with couple-based interventions in improving relationship dynamics and health outcomes, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
The inclusion criteria for couples will be: (a) both partners are males, (b) both partners age over 18, (c) both partners report being a couple for at least three months, (d) one partner is HIV positive and the other partner is HIV-negative (i.e., serodiscordant couples), and (e) both partners are willing to participate.

The exclusion criteria for couples will be: (a) either partner cannot complete the assessment due to a low education level or physical or psychological constraint, and (b) either partner has been diagnosed with another life-threatening disease (e.g., cancer).

Where this trial is running

Chengdu and 3 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Quality of LifeHivRelationship, SocialDyadic CopingSerodiscordant CouplesRandomized Controlled TrialChina
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.