Costotransverse foramen block versus thoracic paravertebral block for pain control after lung cancer thoracotomy
Costotransverse Foramen Block Versus Thoracic Paravertebral Block in Thoracotomy for Lung Cancer: A Randomized Controlled Trial
This will test whether the costotransverse foramen block or the thoracic paravertebral block gives better pain relief for adults having thoracotomy for lung cancer.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 70 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | National Cancer Institute, Egypt Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT07367581 on ClinicalTrials.gov |
What this trial studies
Thoracotomy causes severe postoperative pain and reliable pain control is a major clinical challenge. This study compares a newer nerve block technique, the costotransverse foramen block (CTFB), with the established thoracic paravertebral block (TPVB) in patients undergoing thoracotomy for lung cancer. Eligible patients will receive either CTFB or TPVB as part of their perioperative analgesia and investigators will track postoperative pain scores, opioid consumption, and complications. The aim is to see if CTFB can match or improve pain control while reducing side effects and opioid use.
Who should consider this trial
Good fit: Adults 18–65 years old with ASA physical status II–III, BMI 18–35 kg/m2, and scheduled for thoracotomy for lung cancer who can consent are the ideal candidates.
Not a fit: Patients with contraindications to regional anesthesia, severe organ failure, morbid obesity, chronic pain therapy, or inability to cooperate are unlikely to gain benefit from this comparison.
Why it matters
Potential benefit: If successful, CTFB could provide comparable or better pain relief with fewer side effects and lower opioid needs, improving recovery after thoracotomy.
How similar studies have performed: CTFB is a recently described technique with mainly cadaver and case report data so far, whereas TPVB and other regional blocks have established evidence for thoracotomy pain control.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 18 years and ≤ 65 years old. * American Society of Anesthesiologists (ASA) physical status II-III. * Body mass index 18-35 kg/m2. * Patients scheduled for thoracotomies for lung cancer. Exclusion Criteria: * Patient refusal. * History of sensitivity to local anesthetics. * History of psychological disorders. * Contraindication to regional anesthesia, e.g., local sepsis, pre-existing peripheral neuropathies, and coagulopathy. * Severe respiratory, cardiac, hepatic, or renal disease. * Morbid obesity. * Uncooperative patients. * Patients on chronic pain therapy.
Where this trial is running
Cairo
- Cairo University — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Mai M Elrawas, MD
- Email: mai.elrawas@nci.cu.edu.eg
- Phone: 00201222177242
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.