Corticosteroid injection to reduce pain after hip replacement

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of periarticular corticosteroid injection during hip replacement surgery to reduce postoperative pain and shorten hospital stays. The intervention involves administering dexamethasone, a steroid, to patients undergoing unilateral cemented hip endoprosthesis for femoral neck fractures. The goal is to improve pain management, decrease the need for analgesics, and ultimately reduce healthcare costs associated with prolonged hospitalization. The study aims to build on previous findings that suggest steroid supplementation can enhance recovery outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients undergoing unilateral cemented hip endoprosthesis for femoral neck fracture
* Patients aged 50-90 years old
* Patients with a BMI \>18.5 and \<35
* Patients able to provide informed consent and follow all the study procedures as indicated by the protocol
* Informed Consent as documented by signature

Exclusion Criteria:

* Contraindications to steroids
* Revision endoprosthesis
* Active steroid or immunosuppressive therapy in the last 30 days before the operation
* Pregnant or breast-feeding women
* Presence of other clinically significant concomitant disease states (ASA IV)
* Uncontrolled diabetes mellitus
* Contraindications to NSAIDs
* Chronic systemic diseases as immunodeficiency, autoimmune disease (Systemic Lupus Erythematosus, SLE), gout, rheumatic arthritis
* Known or suspected non-compliance, drug or alcohol abuse
* Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant.
* Participation in another study with investigational drug within the 30 days preceding and during the present study
* Previous enrolment into the current study
* Enrolment of the investigator, his/her family members, employees and other dependent persons.

Where it's running

• Christian Candrian
  Lugano, Switzerland Recruiting

Study contacts

• Principal investigator: Christian MD Candrian, Prof. — Eoc
• Study coordinator: Christian MD Candrian, Prof.
• Email: Gabriela.Induni-Lang@eoc.ch
• Phone: 0041918117029

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.