Corticosteroid injection for knee osteoarthritis pain relief after embolization
Role of Intra-articular Corticosteroid Injection in Geniculate Artery Embolization for Knee Osteoarthritis: A Comparative Study
NA · Zagazig University · NCT06514716
This study is testing if adding a corticosteroid injection can help people with knee osteoarthritis feel less pain and move better after a specific procedure called embolization.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Zagazig University (other gov) |
| Locations | 1 site (Zagazig) |
| Trial ID | NCT06514716 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness and safety of intra-articular corticosteroid injection (IACI) in reducing post-procedural pain and improving outcomes in patients with knee osteoarthritis undergoing geniculate artery embolization (GAE). Participants will be randomized into two groups: one receiving GAE with IACI and the other receiving GAE alone. Pain levels will be assessed using the Visual Analog Scale (VAS) at multiple time points, and functional outcomes will be measured using established scoring systems. The study aims to determine if the addition of IACI enhances pain relief and functional improvement compared to GAE alone.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older diagnosed with knee osteoarthritis who are eligible for geniculate artery embolization.
Not a fit: Patients with contraindications to corticosteroid injections or geniculate artery embolization, or those with severe comorbid conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve pain management and functional outcomes for patients with knee osteoarthritis.
How similar studies have performed: While the specific combination of GAE and IACI is novel, similar studies have shown that corticosteroid injections can provide pain relief in osteoarthritis.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 years and older * Diagnosed with knee osteoarthritis (OA) based on clinical and radiographic criteria. * Eligible for geniculate artery embolization (GAE) as determined by the treating physician. * Able to provide informed consent and comply with the study protocol. Exclusion Criteria: * Contraindications to corticosteroid injections or geniculate artery embolization. * Pregnant or breastfeeding women. * Active infection or skin condition at the injection site. * Severe cardiovascular, renal, or hepatic diseases that may affect study participation. * Previous knee surgery within the last 6 months. * Participation in another clinical trial within the last 30 days. * Inability to comply with follow-up visits or complete study assessments.
Where this trial is running
Zagazig
- Zagazig University, Faculty of Medicine — Zagazig, Egypt (RECRUITING)
Study contacts
- Principal investigator: Ahmed A Bessar, MD, PhD — Assistant Professor of Diagnostic and Interventional Radiology, Zagazig Uni.
- Study coordinator: Ahmed A Bessar, MD, PhD
- Email: Ahmedawadbessar@gmail.com
- Phone: +201000089595
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Knee Osteoarthritis, Pain, Musculoskeletal, Geniculate Artery Embolization, Intra-articular Corticosteroid Injection, Pain Relief, Functional Improvement