Clinical trial Recruiting at 1 site Interventional Ages 45 to 60

Core strengthening with pelvic PNF to improve trunk control and balance after sub-acute ischemic stroke

Official title: Effects of Core Strengthening With Pelvic Proprioceptive Neuromuscular Facilitation on Trunk Control and Balance in Patients With Sub-acute Stroke

Run by Lahore University of Biological and Applied Sciences · NCT07381491 · Data updated 2026-11-12

This will test whether adding pelvic proprioceptive neuromuscular facilitation (PNF) to core strengthening and standard trunk exercises improves trunk control and balance in people aged 45–60 recovering from a sub-acute ischemic stroke.

More Stroke trials

Quick facts

Study typeInterventional
Ages45 Years to 60 Years
SexAll
Enrollment38 (estimated)
SponsorLahore University of Biological and Applied Sciences
Academic / other
Locations1 site (Rawalpindi, Punjab Province)
StatusRecruiting
StartedNovember 25, 2025
Main results expectedMay 25, 2026
Study endsMay 30, 2026
Registry record updatedFebruary 2, 2026
Trial IDNCT07381491 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are people aged 45–60 with a first unilateral ischemic stroke in the sub-acute phase (2 weeks to 6 months), able to walk for 2–4 minutes, with mild-to-moderate spasticity (Modified Ashworth Scale 1–2) and an MMSE ≥24.

Probably not a fit

Patients with recurrent stroke, brainstem or cerebellar or hemorrhagic stroke, severe spasticity (MAS ≥3), significant cognitive impairment, or who cannot attend frequent hospital sessions are unlikely to benefit from this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants with unilateral sub-acute ischemic stroke are assigned to either an intervention group receiving pelvic PNF plus core stabilization and conventional trunk-control exercises or a control group receiving conventional trunk-control exercises alone. Sessions are delivered once daily, five days per week for six weeks, with each session lasting about 60 minutes and following a specified FITT schedule of sets, repetitions, and rest periods; PNF sequences include rhythmic initiation, slow reversal, and agonistic reversals. Core stabilization uses biofeedback-guided trunk curls and timed repetitions, and PNF techniques are applied in timed sets with stopwatch monitoring. Outcomes focus on changes in trunk control and balance after the 6-week program.

Why it matters

Potential benefit: If successful, adding pelvic PNF could improve trunk stability and balance, leading to better mobility and reduced fall risk during recovery.

How similar studies have gone: Prior small trials and rehabilitation programs using PNF and core-strengthening techniques have reported improvements in trunk control and balance, but evidence is limited and results have been mixed.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants between the ages of 45 and 60 years.
* Sub-acute phase of unilateral ischemic stroke.
* More than two weeks but no more than six months were included.
* Participants should be able to walk with or without support for 2-4 min.
* Participants with modified Ashworth scale grade 1 or grade 2.
* Participants should be able to understand and follow simple verbal instructions (Mini-Mental Status Examination \[MMSE\]≥24).

Exclusion Criteria:

* Participants with recurrent stroke; brainstem or cerebellar stroke or hemorrhagic stroke.
* Participants with modified Ashworth scale grade ≥3 (severe spasticity).

Where it's running

  • Ghurki Trust & Teaching Hospital
    Rawalpindi, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.