Clinical trial Recruiting at 1 site Interventional Ages 45 to 65 Women only

Core stabilization plus knee exercises for women with knee osteoarthritis

Official title: Randomized Controlled Study of the Effects of Core Stabilization Exercises in Addition to Knee Exercises in Female Patients With Gonarthrosis

Run by Cumhuriyet University · NCT07482332 · Data updated 2026-11-12

This project will test whether adding six weeks of core stabilization exercises to routine knee physiotherapy helps women aged 40–65 with moderate knee osteoarthritis have less pain and better function.

Quick facts

Study typeInterventional
Ages45 Years to 65 Years
SexWomen only
Enrollment40 (estimated)
SponsorCumhuriyet University
Academic / other
Locations1 site (Sivas)
StatusRecruiting
StartedJanuary 5, 2026
Main results expectedAugust 31, 2026
Study endsSeptember 14, 2026
Registry record updatedMarch 19, 2026
Trial IDNCT07482332 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Women aged 40–65 with Kellgren-Lawrence grade 2–3 knee osteoarthritis, BMI under 30, able to bend knees and hips at least 90 degrees, literate in Turkish, and willing to attend in-person therapy at the study site are the intended participants.

Probably not a fit

Patients with BMI ≥30, recent physical therapy, significant knee or lower-extremity surgery, major neurological/cardiac/respiratory conditions, severe sensory impairments, or inability to attend the site are unlikely to be eligible or to benefit from this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study enrolls women aged 40–65 with Kellgren-Lawrence grade 2–3 knee osteoarthritis. All participants receive 10 days of conventional physiotherapy (hot pack, TENS, ultrasound) and a six-week routine knee exercise program, while the intervention group also performs a six-week core stabilization program. Clinical symptoms and functional capacity are measured before and after the intervention to compare outcomes. The study is conducted at Cumhuriyet University in Sivas, Turkey.

Why it matters

Potential benefit: If successful, adding core stabilization could reduce pain and improve daily function for women with moderate knee osteoarthritis.

How similar studies have gone: Prior physiotherapy research and some smaller trials suggest proximal core strengthening can help lower-limb pain and function, but evidence specifically for knee osteoarthritis is limited and mixed.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Kellgren-Lawrence 2-3 knee osteoarthritis
* Female patient aged 40-65
* Volunteer

Exclusion Criteria:

* Having received physical therapy within the last month
* Presence of neurological, cardiac, and respiratory problems
* Less than 90 degrees of flexion in the knee and hip joints
* Presence of any pathology in the lower extremity that may affect balance and function
* History of lower extremity surgery
* Severe visual, hearing, and speech impairment
* Illiteracy in Turkish
* Body mass index of 30 or higher

Where it's running

  • Sivas Cumhuriyet University
    Sivas, Turkey (Türkiye)
    Recruiting

Study contacts

  • Principal investigator: Eda Yıldırım — Cumhuriyet University
  • Study coordinator: Selvin Balki, Associate Professor, Ph.D.
  • Email: balkipt@gmail.com
  • Phone: +90 346 4870000

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.