Core stabilization plus knee exercises for women with knee osteoarthritis
Official title: Randomized Controlled Study of the Effects of Core Stabilization Exercises in Addition to Knee Exercises in Female Patients With Gonarthrosis
Run by Cumhuriyet University · NCT07482332 · Data updated 2026-11-12
This project will test whether adding six weeks of core stabilization exercises to routine knee physiotherapy helps women aged 40–65 with moderate knee osteoarthritis have less pain and better function.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 45 Years to 65 Years |
| Sex | Women only |
| Enrollment | 40 (estimated) |
| Sponsor | Cumhuriyet University Academic / other |
| Locations | 1 site (Sivas) |
| Status | Recruiting |
| Started | January 5, 2026 |
| Main results expected | August 31, 2026 |
| Study ends | September 14, 2026 |
| Registry record updated | March 19, 2026 |
| Trial ID | NCT07482332 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women aged 40–65 with Kellgren-Lawrence grade 2–3 knee osteoarthritis, BMI under 30, able to bend knees and hips at least 90 degrees, literate in Turkish, and willing to attend in-person therapy at the study site are the intended participants.
✕Probably not a fit
Patients with BMI ≥30, recent physical therapy, significant knee or lower-extremity surgery, major neurological/cardiac/respiratory conditions, severe sensory impairments, or inability to attend the site are unlikely to be eligible or to benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study enrolls women aged 40–65 with Kellgren-Lawrence grade 2–3 knee osteoarthritis. All participants receive 10 days of conventional physiotherapy (hot pack, TENS, ultrasound) and a six-week routine knee exercise program, while the intervention group also performs a six-week core stabilization program. Clinical symptoms and functional capacity are measured before and after the intervention to compare outcomes. The study is conducted at Cumhuriyet University in Sivas, Turkey.
Why it matters
Potential benefit: If successful, adding core stabilization could reduce pain and improve daily function for women with moderate knee osteoarthritis.
How similar studies have gone: Prior physiotherapy research and some smaller trials suggest proximal core strengthening can help lower-limb pain and function, but evidence specifically for knee osteoarthritis is limited and mixed.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Kellgren-Lawrence 2-3 knee osteoarthritis * Female patient aged 40-65 * Volunteer Exclusion Criteria: * Having received physical therapy within the last month * Presence of neurological, cardiac, and respiratory problems * Less than 90 degrees of flexion in the knee and hip joints * Presence of any pathology in the lower extremity that may affect balance and function * History of lower extremity surgery * Severe visual, hearing, and speech impairment * Illiteracy in Turkish * Body mass index of 30 or higher
Where it's running
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Sivas Cumhuriyet University
Sivas, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Eda Yıldırım — Cumhuriyet University
- Study coordinator: Selvin Balki, Associate Professor, Ph.D.
- Email: balkipt@gmail.com
- Phone: +90 346 4870000
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.