Convenient home blood testing for routine diabetes checks (CHARM-D)
Comparability of Analyte Levels, Patient Acceptance and Health Economics Between Self-collected Capillary Blood (In-clinic and Home) and Professionally Collected Venous Blood for HbA1c, Lipids and Thyroid Function in Diabetic Patients
Tameside General Hospital · NCT06695325
The study will test whether adults with type 1 or type 2 diabetes can reliably use a home finger‑prick blood sample mailed to a lab to measure HbA1c, lipids, and thyroid levels instead of clinic venous draws.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Tameside General Hospital (other) |
| Locations | 1 site (Ashton-under-Lyne, Lancs) |
| Trial ID | NCT06695325 on ClinicalTrials.gov |
What this trial studies
CHARM-D is an observational comparison of capillary self-collected finger‑prick samples taken at home with standard venous blood draws performed in clinic for HbA1c, lipid profile, and thyroid function tests. Adult participants with type 1 or type 2 diabetes will perform a home self-collection and send samples to the laboratory, and those results will be directly compared with blood drawn in clinic. The study will measure analytic agreement between sampling methods, record patient acceptance and feasibility of home collection, and estimate economic impacts such as travel and time savings. The project is run at Tameside and Glossop Integrated Care NHS Foundation Trust with collaboration from Roche Diagnostics.
Who should consider this trial
Good fit: Adults aged 18 or older with type 1 or type 2 diabetes who can give informed consent and are able to perform a home finger‑prick blood collection are ideal candidates.
Not a fit: Patients who cannot perform self‑collection, are unable to consent, or require urgent in‑person evaluation are unlikely to benefit from this home-sampling approach.
Why it matters
Potential benefit: If successful, home sampling could make routine diabetes monitoring easier, improve adherence to testing schedules, and reduce the need for clinic visits and travel.
How similar studies have performed: Previous research has shown capillary self-sampling can provide comparable results to venous sampling for HbA1c, lipids, and thyroid tests, though large-scale mailed home-sampling programs are still being evaluated.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult subjects aged 18 years and over at the time of signing the informed consent * Ability to provide Informed consent * Type I and II diabetic patient * Ability to understand written and spoken English * Ability to perform a blood draw at home Exclusion Criteria: * Aged less than 18 years of age * Unable to provide informed consent * Unable to perform a blood draw at home
Where this trial is running
Ashton-under-Lyne, Lancs
- Tameside and Glossop Integrated Care NHS Foundation Trust — Ashton-under-Lyne, Lancs, United Kingdom (RECRUITING)
Study contacts
- Principal investigator: Edward Jude, MD FRCP — Tameside and Glossop Integrated Care NHS Foundation Trust
- Study coordinator: Edward Jude, MD, FRCP
- Email: edward.jude@tgh.nhs.uk
- Phone: +441619224011
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Diabetes Mellitus, Home monitoring, HbA1c, Thyroid function, Lipids