Conjunctival transposition surgery for primary pterygium
Conjunctival Transpositional Pterygium Surgery: A Prospective Single-Arm Interventional Study
NA · Zahedan University of Medical Sciences · NCT07343011
This surgery tries moving and repositioning your own pterygium tissue during the operation to see if it lowers regrowth and keeps the eye surface healthy in adults with primary pterygium.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 70 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Zahedan University of Medical Sciences (other) |
| Locations | 1 site (Zahedan, Sistan and Balochistan) |
| Trial ID | NCT07343011 on ClinicalTrials.gov |
What this trial studies
This prospective single-arm interventional protocol enrolls adults with primary pterygium and performs conjunctival transpositional surgery by mobilizing and repositioning the native pterygium tissue. The technique preserves Tenon's layer, avoids creating a bare sclera, and does not use adjunctive therapies such as mitomycin C or grafting. Participants are followed after surgery to record recurrence rate and functional outcomes including ocular surface health and visual symptoms. Patients with recurrent pterygium, prior ocular surface surgery, active infection, or severe ocular surface disease are excluded.
Who should consider this trial
Good fit: Adults aged 18 years or older with a primary pterygium that involves the cornea and who can provide informed consent are ideal candidates.
Not a fit: Patients with recurrent pterygium, a history of prior ocular surface surgery, active ocular infection, or severe ocular surface disease are unlikely to benefit or be eligible.
Why it matters
Potential benefit: If successful, the technique could reduce pterygium recurrence while preserving conjunctival tissue and avoiding grafts or adjunctive drugs.
How similar studies have performed: Conjunctival-sparing approaches and conjunctival autografts have shown good results in lowering recurrence, but purely transpositional techniques without adjuncts are less widely studied and have limited published outcome data.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 years or older * Primary pterygium involving the cornea * Ability to provide informed consent Exclusion Criteria: * Recurrent pterygium * Previous ocular surface surgery * Active ocular infection or inflammation * Severe ocular surface disease
Where this trial is running
Zahedan, Sistan and Balochistan
- Alzahra Eye Hospital, Zahedan University of Medical Sciences — Zahedan, Sistan and Balochistan, Iran (RECRUITING)
Study contacts
- Study coordinator: Mohammed Arish, MD, FRCS
- Email: mohammad.erish@zaums.ac.ir
- Phone: 09151419155
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pterygium of the Conjunctiva and Cornea