Concentric cycling training during chemotherapy for breast cancer patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of a concentric cycling training program on breast cancer patients undergoing (neo)adjuvant chemotherapy. Patients will be randomly assigned to either a training group, which participates in weekly cycling sessions for 15 weeks, or a control group receiving standard treatment. The goal is to determine if this exercise modality can help maintain or improve physical condition and exercise capacity during chemotherapy. The study focuses on patients receiving a combination of anthracyclines and paclitaxel, which are known to cause significant side effects.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Woman ≥ 18 years old
* Stage I to III breast cancer
* Patient currently planning (neo)adjuvant treatment combining anthracycline-cyclophosphamide and weekly paclitaxel (± trastuzumab)
* Affiliation to a social security system
* Able to speak, read and understand French

Exclusion Criteria:

* No prior chemotherapy treatment
* Any known cardiac or vascular pathology
* Contraindications to physical fitness assessment
* Protected adult
* Psychiatric, musculoskeletal or neurological problems
* Pregnant or breastfeeding woman (NB: this population is already subject to a contraindication to (neo)adjuvant treatment. For women of childbearing age, a betaHCG dosage is already carried out systematically before the start of chemotherapy and information on the need for contraception throughout the chemotherapy period is provided before the start of treatment. As part of this study, only the presence of this test with a negative result at the start of chemotherapy will be checked. inclusion, if available).

Where it's running

• Institut de cancérologie Strasbourg Europe
  Strasbourg, France Recruiting
• Hôpitaux civils de Colmar
  Colmar, France Not yet recruiting

Study contacts

• Principal investigator: BENDER Laura, MD — Institut de cancérologie Strasbourg Europe
• Study coordinator: Joris MALLARD, PhD
• Email: j.mallard@icans.eu
• Phone: 368767419

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.