Computer-based mind and body approach for mild cognitive impairment
Modulation Effects of a Computer-based Multimodal Mind and Body Approach for Mild Cognitive Decline
This study is testing a new computer-based program that combines brain exercises with mind-body techniques to see if it can help people with mild cognitive impairment think better and prevent their condition from getting worse.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | Massachusetts General Hospital Academic / other |
| Locations | 1 site (Charlestown, Massachusetts) |
| Trial ID | NCT06814483 on ClinicalTrials.gov |
What this trial studies
This study aims to develop a computer-based multimodal mind and body approach (cbMMBA) to enhance cognitive function in individuals with mild cognitive impairment (MCI). The intervention combines cognitive training with mind-body techniques, such as Baduanjin, to provide a cost-effective and accessible treatment option. Participants will be assessed for cognitive decline and will engage in either the cbMMBA or a standard cognitive training group. The goal is to improve cognitive function and prevent further decline in MCI patients, particularly those with limited access to traditional therapies.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals experiencing cognitive decline but who are not demented and maintain independence in daily activities.
Not a fit: Patients with severe visual or hearing impairments, significant musculoskeletal conditions, or those with a history of neurological or major psychiatric disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could offer a new, accessible treatment option for patients with mild cognitive impairment, potentially improving their cognitive function and quality of life.
How similar studies have performed: Other studies have shown promise in using mind-body interventions for cognitive improvement, but this specific computer-based approach is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. report of cognitive decline / complaint by the patient, the patient's informant, or the physician; 2. cognitive impairment is confirmed by objective cognitive measures (Montreal Cognitive Assessment (MoCA) and neuropsychological testing), where objective cognitive impairment is defined as poor performance in one or more cognitive measures suggesting deficit in one or more cognitive domains; 3. patient has preserved independence in functional abilities (measured by informant report, completion of Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL) checklists); 4. not demented; Exclusion Criteria: 1. has severe visual or hearing impairment; 2. has pre-existing musculoskeletal or other conditions, which prohibit BDJ performance and / or the application of acupressure at the selected points; 3. has suffered from a neurological disorder (e.g., severe head trauma), psychiatric disease (e.g., major depression), or any other major medical disease that could potentially compromise their cognition; 4. has had prior experience with BDJ or acupressure or relaxation techniques in the past year.
Where this trial is running
Charlestown, Massachusetts
- Massachusetts General Hospital — Charlestown, Massachusetts, United States (Recruiting)
Study contacts
- Study coordinator: Bonnie Wong, PhD
- Email: bonnie.wong@mgh.harvard.edu
- Phone: 6177245708
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.