Compressed continuous suture versus conventional suture for conjunctival graft fixation in pterygium surgery
Official title: Comparison of Compression Continuous Suture Versus Conventional Suture for Autologous Conjunctival Implant Fixation in Primary Pterygium Surgery: a Randomized Controlled Trial
Run by Tianjin Eye Hospital · NCT07244276 · Data updated 2026-11-12
This trial will see if a compressed continuous suture or a conventional suture is better at securing an autologous conjunctival graft and reducing symptoms after primary pterygium surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 30 Years to 70 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Tianjin Eye Hospital Academic / other |
| Locations | 1 site (Tianjin, Tianjin Municipality) |
| Status | Recruiting |
| Started | April 2, 2024 |
| Main results expected | April 2, 2026 |
| Study ends | July 2, 2026 |
| Registry record updated | November 24, 2025 |
| Trial ID | NCT07244276 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients with primary pterygium invading 2–5 mm of the cornea who have not had prior eye surgery, have no active ocular inflammation, and can attend regular follow-up visits.
✕Probably not a fit
Patients with recurrent or pseudopterygium, a history of prior eye surgery, active ocular inflammation, or inability to comply with follow-up are unlikely to benefit from this comparison.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This single-center interventional trial at Tianjin Eye Hospital compares two techniques for fixing autologous conjunctival grafts after excision of primary pterygium: a compressed continuous suture and a conventional suture method. Adults with primary pterygium that invades the cornea by 2–5 mm and without prior eye surgery or active ocular inflammation are eligible. Outcomes include graft stability, postoperative discomfort and inflammation, complications (such as granuloma or hemorrhage), ease and timing of suture removal, and pterygium recurrence. Participants receive one of the two suture techniques during surgery and are followed at scheduled postoperative visits to compare healing, symptoms, and recurrence rates.
Why it matters
Potential benefit: If successful, the compressed continuous suture could reduce postoperative irritation and inflammation, simplify the procedure and suture removal, and lower the chance of pterygium coming back.
How similar studies have gone: Previous research indicates that suture technique and alternatives like fibrin glue can influence comfort and recurrence after pterygium surgery, but direct comparisons of compressed continuous suture versus conventional suture are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Diagnosis of primary pterygium according to diagnostic criteria; 2. The pterygium head invades the cornea by 2-5mm; 3. The patient agrees to the surgical treatment and signs the surgical consent form. Exclusion Criteria: 1. History of previous eye surgery; 2. Have active ocular inflammatory lesions; 3. recurrent and pseudopterygium; 4. The patient refuses surgery or is unable to have regular follow-ups
Where it's running
-
Tianjin Eye Hospital
Tianjin, Tianjin Municipality, China Recruiting
Study contacts
- Study coordinator: Yan Wang, director
- Email: wangyan7143@vip.sina.com
- Phone: 23187165
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.