Comparing wound closure techniques in spine surgery

Assessment of Wound Closure Techniques in Primary Spine Surgery Using SPY Intra-operative Angiography

NA · Mayo Clinic · NCT04396613

This study tests which of three different ways to close wounds after spine surgery helps adults with spinal stenosis heal better.

Quick facts

PhaseNA
Study typeInterventional
Enrollment147 (estimated)
Ages18 Years and up
SexAll
SponsorMayo Clinic (other)
Locations1 site (Rochester, Minnesota)
Trial IDNCT04396613 on ClinicalTrials.gov

What this trial studies

This study investigates the differences in blood flow around wound sites when using three different wound closure techniques in patients undergoing primary spine surgery. The researchers aim to determine which technique may promote better healing and outcomes. Eligible participants include adults with spinal stenosis who require surgical intervention for decompression or fusion. The study will assess the effectiveness of these techniques in a controlled surgical setting.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older with a primary diagnosis of spinal stenosis requiring surgical intervention.

Not a fit: Patients with previous spinal surgery, systemic corticosteroid use, or certain chronic conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved healing and recovery outcomes for patients undergoing spine surgery.

How similar studies have performed: Other studies have explored various wound closure techniques, but this specific comparison in the context of spine surgery is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ≥ 18 years old
* Primary diagnosis of spinal stenosis
* Surgical indication for 1 or 2 level posterior spinal decompression or fusion

Exclusion Criteria:

* Pregnant or Breastfeeding
* Previous posterior spinal surgery
* Systemic corticosteroid use
* Long-term anticoagulation treatment
* Diagnosis of diabetes mellitus
* Diagnosis of peripheral arterial disease
* Current smoker
* Active infection of any kind or chronic infection with HIV, Hepatitis C, or Syphilis
* Iodine Allergy

Where this trial is running

Rochester, Minnesota

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Spinal Injuries

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.