Comparing vision therapy and prism treatment for small-angle esotropia

Accommodation and Vergence Exercises Versus Prism Treatment for Small-angle Acute Acquired Concomitant Esotropia

This study is testing whether vision therapy or prism treatment works better for people aged 10 to 40 with small-angle esotropia to help improve their eye alignment and reduce double vision.

Quick facts

• Phase: Not applicable
• Study type: Interventional
• Enrollment: 100 (estimated)
• Ages: 10 Years to 40 Years
• Sex: All
• Sponsor: Eye & ENT Hospital of Fudan University (Academic / other)
• Locations: 1 site (Shanghai)
• Trial ID: NCT06622044 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to compare the effectiveness of vision therapy versus prism treatment in patients with small-angle acute acquired concomitant esotropia. It is a single-center, randomized controlled trial that focuses on patients aged 10 to 40 years with a deviation angle of less than 15 prism diopters. The study will evaluate how well each treatment alleviates symptoms such as diplopia and improves eye alignment. The trial is particularly relevant given the rising incidence of esotropia associated with increased screen time.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals aged 10 to 40 years with a best-corrected visual acuity of 20/20 and a deviation angle of less than 15 prism diopters.

Not a fit: Patients with organic eye diseases, brain lesions, or those who have previously received esotropia therapy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a non-surgical treatment option for patients suffering from small-angle acute acquired concomitant esotropia.

How similar studies have performed: Other studies have explored treatments for esotropia, but this specific comparison of vision therapy and prism treatment is relatively novel.

Eligibility criteria

Inclusion Criteria:

1. Aged 10-40 years (including 10 years and 40 years);
2. Best-corrected visual acuity no worse than 20/20 for both eyes;
3. Deviation angle less than 15 prism diopters (including 15 prism diopters);

Exclusion Criteria:

1. Organic eye diseases;
2. Lesions of the brain;
3. Receiving esotropia therapy(including surgery and prism treatment)
4. Devation angle reducing more than 10 prism diopters after refractive correction

Where this trial is running

Shanghai

• Eye & ENT Hospital of Fudan University — Shanghai, China (Recruiting)

Study contacts

• Study coordinator: Wen Wen, MD, PhD

Conditions Esotropia; Vision Therapy; Acute Acquired Concomitant Esotropia