Comparing video-assisted surgery to traditional surgery for early-stage lung cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to compare the effectiveness of video-assisted thoracoscopic surgery (VATS) with traditional thoracotomy for patients with early-stage non-small-cell lung cancer (NSCLC). It focuses on patients with solid clinical stage T1N0M0 NSCLC and evaluates whether VATS is non-inferior to thoracotomy in terms of disease-free survival. The study will also assess overall survival, perioperative complications, pain levels, and quality of life. Patients will undergo routine CT scans and additional tests to confirm their clinical stage before being randomized into one of the two surgical approaches.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinical stage T1N0M0 and surgical resectable.
* Solid appearance on computed tomography scan.
* Age 18 to 75 year.
* Signed the informed consent form.

Exclusion Criteria:

* Not NSCLC in pathological analysis.
* Not lobectomy or sublobar resection.
* History of other malignant tumors within 5 years.
* History of thoracic surgery or unsuitable for VATS.
* Previous radiation or chemotherapy.

Where it's running

• Fudan University Shanghai Cancer Center
  Shanghai, China Recruiting

Study contacts

• Principal investigator: Shanghai Cancer Center Chen, Ph.D — Shanghai Cancer Center
• Study coordinator: Haoxuan Wu, M.D.
• Email: haoxuanwu@hotmail.com
• Phone: 86-13901770461

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.