Comparing ultrasound-guided and blinded trigger point injections for myofascial pain

Comparison of Trigger Point Injection Application Methods in Patients With Fibromyalgia Syndrome and Myofascial Pain Syndrome

Not applicable Interventional Firat University · NCT06555523

This study is testing whether ultrasound-guided trigger point injections work better than regular injections for easing pain in the neck and shoulders of people with fibromyalgia.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment20 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorFirat University Academic / other
Locations1 site (Elâzığ)
Trial IDNCT06555523 on ClinicalTrials.gov

What this trial studies

This study compares the effectiveness of ultrasound-guided trigger point injections versus blinded trigger point injections in the trapezius muscle for patients with Fibromyalgia Syndrome (FMS). Seventy-five participants will be randomly assigned to receive one of the two injection types, alongside a standardized home exercise regimen focusing on stretching and posture. The effectiveness of the treatments will be assessed one month post-injection using various evaluation tools, including the Fibromyalgia Impact Questionnaire and Visual Analog Scale for pain. The goal is to deactivate trigger points and alleviate pain associated with FMS.

Who should consider this trial

Good fit: Ideal candidates are adults aged 20-60 diagnosed with Fibromyalgia Syndrome and cervical chronic myofascial pain syndrome.

Not a fit: Patients with cervical radiculopathy, systemic infections, or those who have received treatment for myofascial pain syndrome in the last three months may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide patients with more effective pain relief options for managing myofascial pain syndrome.

How similar studies have performed: Other studies have shown promise in using ultrasound guidance for trigger point injections, suggesting this approach may enhance treatment effectiveness.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged 20-60 years who met the 2013 ACR criteria
* Patients who will be diagnosed with FMS and cervical chronic MAS according to Travel and Simons' criteria
* Patients who had a palpated tense band in the upper trapezius muscle and at least 1 active trigger point

Exclusion Criteria:

* Patients with a diagnosis of cervical radiculopathy, myelopathy, local or systemic infection, treatment for MAS in the last 3 months
* Patients who have symptom duration less than 3 months
* Patients with pregnancy status, acute or chronic disease that would cause clinical confusion at the time of the study

Where this trial is running

Elâzığ

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Injection SiteFibromyalgiaMyofascial pain syndromeInjectionTrigger point
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.