Comparing two ventilation methods for obese patients during laparoscopic bariatric surgery

Comparison Between Individualized PEEP Ventilation Guided by Driving Pressure and Conventional Lung Protective Strategy in Obese Patients Undergoing Laparoscopic Bariatric Surgery: a Prospective Randomized Controlled Trial

NA · Tanta University · NCT06950112

This study is testing two different breathing methods during weight loss surgery to see which one helps obese patients breathe better and stay safe.

Quick facts

PhaseNA
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorTanta University (other)
Locations1 site (Tanta, El Gharbia)
Trial IDNCT06950112 on ClinicalTrials.gov

What this trial studies

This study aims to compare two different ventilation strategies in obese patients undergoing laparoscopic bariatric surgery: individualized PEEP ventilation guided by driving pressure and a conventional lung protective strategy. The effectiveness of these methods will be assessed using lung ultrasound scores to evaluate lung function and safety. The study will include patients with a BMI between 30-40 kg/m2 and ASA physical status II or III, aged 18 to 60 years. The goal is to determine which ventilation approach provides better outcomes for this specific patient population.

Who should consider this trial

Good fit: Ideal candidates for this study are obese patients with a BMI of 30-40 kg/m2 scheduled for laparoscopic bariatric surgery.

Not a fit: Patients with a history of thoracic surgery, chest diseases, or other significant pre-existing conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved respiratory outcomes and safety during bariatric surgery for obese patients.

How similar studies have performed: Other studies have shown promising results with individualized ventilation strategies, suggesting potential benefits in similar patient populations.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. patients who have a BMI 30-40 kg/m2
2. American Society of Anesthesiologists (ASA) physical status II or III
3. patients aged between 18 and 60 years,
4. patients scheduled to undergo laparoscopic bariatric surgeries.

Exclusion Criteria:

1. patients' refusal to participate in the study,
2. previous history of thoracic surgery,
3. Patients with a history of chest disease (COPD, emphysema, or pneumothorax),
4. Patients with abnormal pre-operative chest radiographs, such as pneumonia and pleural effusion,
5. Patients with right-side heart failure or impending failure,
6. Patients with known hypovolemia, and Patients with increased intracranial pressure.

Where this trial is running

Tanta, El Gharbia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Obese Patients With Bariatric Surgery, Lung Ultrasound Score

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.