Comparing two types of video laryngoscopy blades for intubation in neonates and small infants

Standard Versus Hyperangulated Video Laryngoscopy Blades for Intubation in Neonates and Small Infants: Evaluation of the Glottic View

Not applicable Interventional American University of Beirut Medical Center · NCT05843565

This study is testing which of two video laryngoscopy blades works better for safely intubating newborns and small infants during surgery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages1 Month to 3 Months
SexAll
SponsorAmerican University of Beirut Medical Center Academic / other
Locations1 site (Beirut)
Trial IDNCT05843565 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to compare the effectiveness of two video laryngoscopy blades, the hyperangulated Cobalt blade and the straight Miller blade, in achieving a better glottic view during intubation in neonates and small infants. It will enroll 40 participants, all weighing 5 kg or less and aged 3 months or younger, who are scheduled for elective surgery under general anesthesia. The study will assess the percentage of glottic opening (POGO), first attempt success rates, number of attempts, time to successful intubation, and any adverse events during the procedure. Participants will be randomly assigned to receive either blade first, followed by the other blade for comparison.

Who should consider this trial

Good fit: Ideal candidates are neonates or small infants weighing 5 kg or less and aged 3 months or younger, scheduled for elective surgery.

Not a fit: Patients with a history of difficult airway, craniofacial anomalies, or ASA class IV status may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve intubation success rates and reduce complications in neonates and small infants.

How similar studies have performed: While there have been studies on intubation techniques in adults, this specific comparison in neonates and small infants is novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Neonates or small infants with body weight ≤ 5 kg or age ≤ 3 months, scheduled for elective surgery under general anesthesia.
* ASA (American Society of Anesthesiologists) class I-III patients.

Exclusion Criteria:

* Patients with a history of difficult airway or with craniofacial and airway anomalies.
* ASA (American Society of Anesthesiologists) class IV patients.
* Recent respiratory tract infection within the last 2 weeks.

Where this trial is running

Beirut

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions IntubationDifficult or FailedLaryngoscopyPediatricsNeonates
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.