Comparing two types of varnish for treating tooth sensitivity

Clinical Evaluation of Giomer Based Varnish Versus CPP-ACP Varnish in the Management of Dentin Hypersensitivity: a Randomized Clinical Trial

Not applicable Interventional Cairo University · NCT06154941

This study is testing which type of varnish works better to relieve tooth sensitivity in people aged 18 to 40 who have pain from sensitive teeth.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 40 Years
SexAll
SponsorCairo University Academic / other
Locations1 site (Cairo)
Trial IDNCT06154941 on ClinicalTrials.gov

What this trial studies

This clinical evaluation compares the effectiveness of giomer-based varnish and CPP-ACP varnish in managing dentin hypersensitivity, a common dental issue affecting many patients. The study involves participants aged 18 to 40 who experience pain from dentin hypersensitivity in at least one tooth. By utilizing two different varnish treatments, the trial aims to determine which method is more effective in reducing sensitivity by either nerve desensitization or physically occluding the dentinal tubules. The study is conducted at the Faculty of Dentistry at Cairo University.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 18 to 40 with good oral hygiene who experience pain due to dentin hypersensitivity.

Not a fit: Patients who have received desensitizing treatment in the last 6 months, are taking anti-inflammatory drugs, are pregnant, or are smokers may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a more effective treatment option for patients suffering from dentin hypersensitivity.

How similar studies have performed: Previous studies have shown varying success with different varnish treatments for dentin hypersensitivity, but this specific comparison is novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants of both genders aged 18 to 40 years with good oral hygiene, suffering from pain due to dentin hypersensitivity in at least one tooth

Exclusion Criteria:

* Taking desensitizing treatment in the last 6 months. (It affects the outcome)

  * Taking anti-inflammatory drugs. (It affects the hypersensitivity perception)
  * Pregnant females. ( They complain from nausea and repeated vomiting attacks)
  * Smokers. (Smoking will affect the oral hygiene and periodontal health)

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Dentin Hypersensitivity
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.