Comparing two types of therapy for improving arm function after stroke

Comparative Effects of Intensive and Distributed Constraint-induced Movement Therapy on Upper Extremity Function in Stroke Patients

NA · Riphah International University · NCT06459336

This study is testing two different ways of therapy to see which one helps stroke patients improve their arm function better.

Quick facts

PhaseNA
Study typeInterventional
Enrollment50 (estimated)
Ages45 Years to 65 Years
SexAll
SponsorRiphah International University (other)
Locations1 site (Lahore, Punjab Province)
Trial IDNCT06459336 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effects of two different protocols of constraint-induced movement therapy (CIMT) on upper extremity function in stroke patients. Participants will either undergo an intensive CIMT protocol for 6 hours a day over 6 days or a distributed CIMT protocol for 2.25 hours twice a week over 8 weeks, both totaling 36 hours of therapy. The study aims to determine if these two approaches yield similar improvements in motor outcomes for patients recovering from stroke. This research addresses a gap in existing literature regarding the comparative effectiveness of these CIMT protocols.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 40-70 who have experienced a stroke and have specific motor function capabilities.

Not a fit: Patients with severe systemic illnesses, epilepsy, or recent interventions on the upper extremity may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into the most effective therapy approach for improving arm function in stroke patients.

How similar studies have performed: While many studies have explored CIMT, this specific comparative approach is novel and has not been directly tested before.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 40-70 years
* ischemic or hemorrhagic stroke
* Both genders eligible
* Gcs score ≥ 13
* Able to extend at least 10° at the fingers
* Able to extend at least 20° at the wrist
* Patients diagnosed with one side more affected(hemiplegia)
* Modified Ashworth scale score ≤2

Exclusion Criteria:

* severe, chronic systemic illness
* Epilepsy
* History of fall past 6 months
* Injections of botulinum toxin type A or operations on the UE within 6 months

Where this trial is running

Lahore, Punjab Province

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Stroke, upper extremity function

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.