Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Comparing two types of stitches for surgical wounds

Official title: Outcomes of Running Locking Suture vs Standard Running Suture in Surgical Wounds: a Randomized Evaluator-blinded Split-wound Comparative Effectiveness Trial

Run by University of California, Davis · NCT06288009 · Data updated 2026-11-12

This study is testing whether using a special type of stitch or a standard stitch after surgery on the head and neck leads to less scarring and better-looking results for patients.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment50 (estimated)
SponsorUniversity of California, Davis
Academic / other
Locations1 site (Sacramento, California)
StatusRecruiting
StartedAugust 1, 2024
Main results expectedAugust 1, 2026
Study endsOctober 1, 2026
Registry record updatedDecember 5, 2025
Trial IDNCT06288009 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older scheduled for cutaneous surgical procedures on the head or neck requiring primary closure.

Probably not a fit

Patients with wounds shorter than 3cm or those who are pregnant or incarcerated may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the effectiveness of running locking sutures versus standard running sutures in reducing scarring after surgical procedures on the head and neck. Patients undergoing cutaneous surgery will have one side of their wound closed with standard sutures and the other side with locking sutures. The goal is to evaluate which technique results in less scarring and better aesthetic outcomes. By analyzing the healing process and post-operative complications, the study aims to provide insights into optimal wound closure methods.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical techniques that minimize scarring for patients undergoing facial and head surgeries.

How similar studies have gone: While there have been studies on various suturing techniques, the specific comparison of running locking sutures to standard running sutures for scar reduction is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years of age or older
* Able to give informed consent themselves
* Patient scheduled for cutaneous surgical procedure on the head or neck with predicted primary closure
* Willing to return for follow up visit

Exclusion Criteria:

* Incarceration
* Under 18 years of age
* Pregnant Women
* Unable to understand written and oral English
* Wounds with predicted closure length less than 3cm

Where it's running

  • University of California, Davis - Dermatology Department
    Sacramento, California, United States
    Recruiting

Study contacts

  • Principal investigator: Daniel Eisen, MD — University of California, Davis - Dermatology
  • Study coordinator: John Robb, BS, BA
  • Email: jmrobb@ucdavis.edu
  • Phone: 9165512636

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.