Comparing two types of steroid injections for De Quervain's Tenosynovitis
Official title: Intra-sheath vs Extra-sheath Injection for De Quervain's Tenosynovitis
Run by University of California, Davis · NCT04895956 · Data updated 2026-11-12
This study is testing whether steroid injections given inside or outside the tendon sheath work better to relieve pain for people with De Quervain's Tenosynovitis.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | University of California, Davis Academic / other |
| Locations | 1 site (Sacramento, California) |
| Status | Recruiting |
| Started | January 24, 2022 |
| Main results expected | September 1, 2026 |
| Study ends | September 1, 2026 |
| Registry record updated | July 6, 2026 |
| Trial ID | NCT04895956 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals diagnosed with De Quervain's Tenosynovitis who have a pre-injection pain score of at least 40mm.
✕Probably not a fit
Patients who have previously undergone steroid injections or surgery for De Quervain's in the affected wrist may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to compare the effectiveness of intra-sheath versus extra-sheath steroid injections in treating De Quervain's Tenosynovitis. Patients will be randomly assigned to receive either type of injection, and their pain levels will be assessed using a visual analog scale before and six weeks after the injection. The study will evaluate whether extra-sheath injections are inferior to intra-sheath injections in reducing pain associated with this condition. The results will help determine the most effective injection technique for managing De Quervain's Tenosynovitis.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment options for patients suffering from De Quervain's Tenosynovitis.
How similar studies have gone: Other studies have explored steroid injection techniques for similar conditions, but this specific comparison of intra-sheath versus extra-sheath injections is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Signed informed consent from the patient exclusively and not a legal representative * Clinically diagnosed with De Quervain's * VAS score of at least 40mm pre-injection * Life expectancy greater than 1 year Exclusion Criteria: * Having previously undergone steroid injection in the treatment of De Quervain's * Having previously undergone surgery for De Quervain's in the affected wrist * Having previously undergone steroid injection and failed in the treatment of trigger finger * Allergies to lidocaine or dexamethasone * Underlying serious medical conditions that would place the patient at risk * Past history of hypothyroidism or rheumatoid arthritis * Pregnant women * Prisoners
Where it's running
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UC Davis Health, Department of Orthopaedics
Sacramento, California, United States Recruiting
Study contacts
- Principal investigator: Christopher O Bayne, MD — University of California, Davis
- Study coordinator: Julia Martin, MS
- Email: jyhmartin@ucdavis.edu
- Phone: 916-7348175
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Comparing standard physiotherapy and eccentric exercises for de Quervain's disease treatment
This study tests whether standard physiotherapy or a special exercise program can help people with de Quervain's disease feel less pain and improve their daily activities.
-
Using gel aromatherapy to relieve pain in patients with De Quervain disease
This study is testing if a new aromatherapy gel can help relieve pain in people with De Quervain disease better than the usual diclofenac gel.
-
Comparing two training methods for treating De Quervain Tenosynovitis
This study is testing which of two training methods works better for people with De Quervain Tenosynovitis to help them feel better.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.