Comparing two types of nerve blocks for pain relief after shoulder surgery

Comparison Between Ultrasound Guided Pericapsular Nerve Group (PENG) Block and Interscalene Brachial Plexus Block for Postoperative Analgesia Following Shoulder Arthroscopy: Prospective, Randomized Controlled Trial

NA · Ain Shams University · NCT06235879

This study tests which type of nerve block, either the PENG block or the interscalene block, works better for relieving pain after shoulder surgery.

Quick facts

PhaseNA
Study typeInterventional
Enrollment50 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorAin Shams University (other)
Locations1 site (Cairo)
Trial IDNCT06235879 on ClinicalTrials.gov

What this trial studies

This study compares the effectiveness of ultrasound-guided pericapsular nerve group (PENG) block versus interscalene brachial plexus block for managing postoperative pain following shoulder arthroscopy. Shoulder arthroscopy is a minimally invasive procedure that can lead to significant postoperative pain in many patients. The study aims to determine which nerve block technique provides better analgesia while minimizing complications associated with the traditional interscalene block. By evaluating pain relief and side effects, the research seeks to improve postoperative care for patients undergoing shoulder surgery.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 to 60 years with a BMI of 35 or less, scheduled for elective unilateral arthroscopic shoulder surgery.

Not a fit: Patients with significant respiratory diseases, neurological disorders, or those who do not meet the eligibility criteria may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management techniques for patients undergoing shoulder arthroscopy, enhancing recovery and patient satisfaction.

How similar studies have performed: Previous studies have shown promising results with peripheral nerve blocks for postoperative analgesia, but the PENG block is a newer approach that requires further investigation.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

- Age from 18 to 60 years old. - Both genders. - BMI ≤35 kg/m2. - American Society of Anesthesiologists Physical Status (ASA-PS) Class I and II. - Patient who will be scheduled for an elective unilateral arthroscopic shoulder surgery.

Exclusion Criteria:

* Refusal of procedure or participation in the study
* Patient under age of 18 years old or above 60 years' old
* Physical status: ASA-PS III or above.
* Pregnancy or lactation.
* Infection at site of injection.
* Psychiatric illness.
* CNS Diseases like (epilepsy, stroke ...etc.) or neurological disease affecting patient's upper limb.
* Evidence of coagulopathy or anticoagulation.
* Patients with respiratory disease, renal or hepatic insufficiency.
* infection of the skin in the puncture area.
* Allergy against any of the drugs to be used.
* Obesity (BMI \>35 kg/m2).

Where this trial is running

Cairo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Pericapsular Nerve Block, Interscalene Brachial Plexus Block, Shoulder Arthroscopy

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.