Comparing two types of lasers for treating hair loss
Comparison of an Non-ablative Fractional 1565nm vs. an Ablative 2940-nm Fractional Erbium-glass Laser for the Treatment of Male Androgenetic Alopecia
This study is testing which of two different laser treatments works better for helping people with hair loss grow more hair and feel satisfied with the results.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 135 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | Male |
| Sponsor | Second Affiliated Hospital, School of Medicine, Zhejiang University Academic / other |
| Locations | 1 site (Hangzhou, Zhejiang) |
| Trial ID | NCT06218498 on ClinicalTrials.gov |
What this trial studies
This study compares the effectiveness and safety of two laser treatments for androgenetic alopecia: an ablative fractional 2940-nm erbium yttrium aluminum garnet (Er: YAG) laser and a non-ablative fractional 1565nm laser. Participants will be evaluated based on hair count, hair diameter, and patient satisfaction at 12 and 24 weeks post-treatment. The study aims to determine which laser treatment is more effective in promoting hair regrowth. Adverse events will also be monitored throughout the study.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 65 with a clinical diagnosis of androgenetic alopecia classified as Norwood Hamilton grade II-V.
Not a fit: Patients with severe internal organ diseases, skin infections, or those who have received recent immunosuppressive treatments may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more effective laser treatment option for patients suffering from androgenetic alopecia.
How similar studies have performed: While laser treatments have shown promise in hair regrowth, this specific comparison of ablative versus non-ablative lasers is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * age between 18 and 65 years;； * clinical diagnosis of AGA； * AGA diagnosis was evaluated following Norwood Hamilton grade II-V criteria； * no previous laser treatments for AGA in the past six months before enrollment； * willingness to provide pictures and follow-up studies. Exclusion Criteria: * if presented with severe diseases of internal organs, eyes, or skin; * inflammation, infection, or unhealed wounds on the skin around the site of treatment on the head; * systematic treatment with corticosteroids or other immunosuppressants and immunomodulators in the past 3 months
Where this trial is running
Hangzhou, Zhejiang
- Second Affiliated Hospital, School of Medicine, Zhejiang University, China — Hangzhou, Zhejiang, China (Recruiting)
Study contacts
- Principal investigator: Xianjie Wu, Ph.D — Second Affiliated Hospital, School of Medicine, Zhejiang University
- Study coordinator: Ru Dai
- Email: dairu@zju.edu.cn
- Phone: +8615982215914
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.