Comparing two types of grafts for treating gum recession in the upper jaw
Comparison of Subepithelial Connective Tissue Grafts Harvested from the Maxillary Tuberosity or Lateral Palate in the Treatment of Single Maxillary Recession-type Defects
NA · Gazi University · NCT06404762
This study is testing which of two types of gum grafts works better and is more comfortable for people with gum recession in the upper jaw.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Gazi University (other) |
| Locations | 1 site (Ankara, Çankaya) |
| Trial ID | NCT06404762 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness and patient comfort of two different types of subepithelial connective tissue grafts (SCTG) harvested from the maxillary tuberosity and the lateral palate, when used in conjunction with a coronally advanced flap (CAF) to treat single maxillary recession-type defects. A total of 30 patients will be randomly assigned to receive either graft type, and their root coverage outcomes and postoperative morbidity will be assessed. Additionally, the study will analyze the histological characteristics of the grafts from both harvesting sites to determine any differences. The findings could provide insights into the best practices for periodontal plastic-aesthetic surgeries.
Who should consider this trial
Good fit: Ideal candidates for this study are non-smoking, systemically healthy individuals with isolated maxillary anterior and premolar teeth experiencing mild to moderate gingival recession.
Not a fit: Patients with active periodontal disease, significant medical contraindications, or those who smoke may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment options for patients with gum recession, resulting in better outcomes and reduced postoperative discomfort.
How similar studies have performed: Previous studies have indicated that grafts harvested from the maxillary tuberosity may provide similar or better outcomes compared to traditional harvesting sites, suggesting a promising avenue for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Non-smoker, systemically healthy * No active periodontal disease * Maxillary anterior and premolar teeth with single, isolated recessions RT 1 (Miller 1 \&2) * Absences of non-carious cervical lesions (NCCL) and non-detectable cemento-enamel junction (CEJ) * Buccal gingival recession defects between 2-5 mm in depth Exclusion Criteria: * Presence of caries lesions or restorations in the cervical area * Intake of medications that impede periodontal tissue health and healing * Medical contraindications for periodontal surgical procedures * Pregnancy and lactation * Bleeding and plaque scores ≥ 20% * Probing depths \> 4 mm
Where this trial is running
Ankara, Çankaya
- Gazi University Faculty of Dentistry — Ankara, Çankaya, Turkey (RECRUITING)
Study contacts
- Study coordinator: Assoc Prof Dr, PhD
- Email: silaisler@gazi.edu.tr
- Phone: +905069966074
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Gingival Recession, Localized, Maxillary Tuberosity, Connective Tissue Graft, Coronally Advanced Flap