Comparing two types of digital breast imaging for better detection of abnormalities

Comparison of Conspicuity of Masses and Architectural Distortions Between Wide- and Narrow-angle Digital Breast Tomosynthesis Systems

Observational M.D. Anderson Cancer Center · NCT06373354

This study is testing whether wide-angle digital breast imaging can find more breast abnormalities than narrow-angle imaging for women getting routine mammograms.

Quick facts

Study typeObservational
Enrollment100 (estimated)
SexFemale
SponsorM.D. Anderson Cancer Center Academic / other
Locations1 site (Houston, Texas)
Trial IDNCT06373354 on ClinicalTrials.gov

What this trial studies

This study aims to compare the effectiveness of narrow-angle and wide-angle digital breast tomosynthesis (DBT) in detecting masses and architectural distortions in breast tissue. The primary objective is to demonstrate that wide-angle DBT images provide superior visibility of lesions compared to narrow-angle images. Additionally, the study will gather feedback from radiologists and technologists, as well as assess participant comfort during the imaging process. The research is observational and focuses on standard screening mammography patients.

Who should consider this trial

Good fit: Ideal candidates for this study are women undergoing standard screening mammography who can understand and sign consent.

Not a fit: Patients who are pregnant, unable to consent, or male will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved detection of breast abnormalities, enhancing early diagnosis and treatment options for patients.

How similar studies have performed: While this approach is innovative, similar studies have shown promise in improving imaging techniques, suggesting potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Women undergoing standard screening mammography.
* Ability to understand and sign consent.

Exclusion Criteria:

* Pregnant women.
* Women unable to consent.
* Male patients.

Where this trial is running

Houston, Texas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Architectural DistortionsBreast Tomosynthesis
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.